Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.73 |
| ▸ | PRKCG | P05129 | 2/20 | 0.73 |
| ▸ | PRKCB | P05771 | 2/20 | 0.73 |
| ▸ | PRKCA | P17252 | 2/20 | 0.73 |
| ▸ | PRKCH | P24723 | 2/20 | 0.73 |
| ▸ | PRKCI | P41743 | 2/20 | 0.73 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.73 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.73 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.73 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.73 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.73 |
| ▸ | GMNN | O75496 | 1/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.73 |
| ▸ | BLM | P54132 | 1/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.73 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14447847 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL27603790 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL29464127 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL8257173 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| Edelfosine SCHEMBL8251942 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| SCHEMBL23016734 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| Edelfosine SCHEMBL4177817 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| Edelfosine SCHEMBL1962471 | 1.00 | AKT1 (0.73) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| Edelfosine SCHEMBL28728461 | 0.94 | AKT1 (0.65) | AKT1PRKD3PRKCGPRKCBPRKCA | |
| Edelfosine SCHEMBL28728460 | 0.94 | AKT1 (0.65) | AKT1PRKD3PRKCGPRKCBPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016094226-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | GLYCOREGIMMUNE, INC. (US) | 2016-06-16 | — | — | WO | disclosed |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | ALTIUM GROWTH FUND, LP | 2016-06-09 | — | — | US | disclosed |
| US-7998945-B2 | Methods for the treatment and amelioration of atopic dermatitis | JADO TECHNOLOGIES GMBH (DE) | 2011-08-16 | — | — | US | disclosed |
| US-7998945-B2 | Methods for the treatment and amelioration of atopic dermatitis | JADO TECHNOLOGIES GMBH (DE) | 2011-08-16 | — | — | US | disclosed |
| US-20090018105-A1 | Means and Methods for the Treatment and Prevention of Allergic Diseases | JADO TECHNOLOGIES GMBH | 2009-01-15 | — | — | US | disclosed |
| US-20090018105-A1 | Means and Methods for the Treatment and Prevention of Allergic Diseases | JADO TECHNOLOGIES GMBH | 2009-01-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090018105-A1 | Means and Methods for the Treatment and Prevention of Allergic Diseases | PHOSPHO1, CPA3, SMPD3 | AKT1 1146/4885PRKD3 283/4885PRKCG 355/4885 |
| US-20160158258-A1 | PREVENTION AND TREATMENT OF INFLAMMATORY CONDITIONS | RXRA, RXRG, CX3CR1 | AKT1 2455/4885PRKD3 1335/4885PRKCG 596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.