Edelfosine

Edelfosine

SCHEMBL1962471

CCCCCCCCCCCCCCCCCCOC[C@H](COP(=O)(O)OCC[N+](C)(C)C)OC

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ AKT1 P31749 3/20 0.73
▸ PRKD3 O94806 2/20 0.73
▸ PRKCG P05129 2/20 0.73
▸ PRKCB P05771 2/20 0.73
▸ PRKCA P17252 2/20 0.73
▸ PRKCH P24723 2/20 0.73
▸ PRKCI P41743 2/20 0.73
▸ PRKCE Q02156 2/20 0.73
▸ PRKCQ Q04759 2/20 0.73
▸ PRKCZ Q05513 2/20 0.73
▸ PRKCD Q05655 2/20 0.73
▸ PRKD1 Q15139 2/20 0.73
▸ ALDH1A1 P00352 1/20 0.73
▸ MAPK1 P28482 1/20 0.73
▸ SMN1; SMN2 Q16637 1/20 0.73
▸ MEN1 O00255 1/20 0.73
▸ GMNN O75496 1/20 0.73
▸ LMNA P02545 1/20 0.73
▸ BLM P54132 1/20 0.73
▸ KMT2A Q03164 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14447847 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
SCHEMBL27603790 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
SCHEMBL12380305 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
SCHEMBL29464127 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
SCHEMBL8257173 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
Edelfosine SCHEMBL8251942 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
SCHEMBL23016734 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
Edelfosine SCHEMBL4177817 1.00 AKT1 (0.73) AKT1PRKD3PRKCGPRKCBPRKCA
Edelfosine SCHEMBL28728461 0.94 AKT1 (0.65) AKT1PRKD3PRKCGPRKCBPRKCA
Edelfosine SCHEMBL28728460 0.94 AKT1 (0.65) AKT1PRKD3PRKCGPRKCBPRKCA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260005070-A1 DICING SYSTEM AND DICING METHOD PANASONIC IP MAN CO LTD (JP) 2026-01-01 — — US disclosed
US-12438051-B2 Dicing system and dicing method PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2025-10-07 — — US disclosed
US-12185150-B2 Communication apparatus and communication method for measuring a channel quality indicator (CQI) SUN PATENT TRUST (US) 2024-12-31 — — US disclosed
CN-117935825-A Interactive unrestricted voice enhancement method, system and terminal based on ultrasonic sensing 上海交通大学 2024-04-26 — — CN disclosed
US-20240114377-A1 COMMUNICATION APPARATUS AND COMMUNICATION METHOD FOR MEASURING A CHANNEL QUALITY INDICATOR (CQI) SUN PATENT TRUST (US) 2024-04-04 — — US disclosed
US-11889340-B2 Communication apparatus and communication method for measuring a channel quality indicator (CQI) SUN PATENT TRUST (US) 2024-01-30 — — US disclosed
US-20230189043-A1 COMMUNICATION APPARATUS AND COMMUNICATION METHOD FOR MEASURING A CHANNEL QUALITY INDICATOR (CQI) SUN PATENT TRUST (US) 2023-06-15 — — US disclosed
WO-2023086465-A1 COMPOSITIONS FOR THE DELIVERY OF PAYLOAD MOLECULES TO AIRWAY EPITHELIUM MODERNATX, INC. (US) 2023-05-19 — — WO disclosed
US-11582630-B2 Communication apparatus and communication method for measuring a channel quality indicator (CQI) SUN PATENT TRUST (US) 2023-02-14 — — US disclosed
US-11529361-B2 Halogenated salicylanilides for treating Clostridium infections UNION therapeutics A/S (DK) 2022-12-20 — — US disclosed
WO-2022249226-A1 ROBOT TEACHING DEVICE, ROBOT CONTROL SYSTEM, ROBOT TEACHING METHOD, AND ROBOT TEACHING PROGRAM 三菱電機株式会社 2022-12-01 — — WO disclosed
WO-2022244577-A1 ILLUMINATION ADJUSTING DEVICE, ILLUMINATION ADJUSTING METHOD, AND PRODUCT RECOGNITION SYSTEM パナソニックIPマネジメント株式会社 2022-11-24 — — WO disclosed
CN-114450779-A Cutting system and cutting method 松下知识产权经营株式会社 2022-05-06 — — CN disclosed
US-20110144137-A1 METHOD FOR PREVENTING OR ALLEVIATING THE NOXIOUS EFFECTS RESULTING FROM TOXICANT EXPOSURE YALE UNIVERSITY (US) 2011-06-16 — — US disclosed
CN-101439016-A Bendamustine and potentiating agent thereof carried by anti-cancer medicine sustained-release injection JINAN SHUAIHUA PHARMACEUTICAL (CN) 2009-05-27 — — CN disclosed
CN-101332181-A Anticancer composition containing irinotecan JINAN SHUAIHUA MEDICINE SCIENC (CN) 2008-12-31 — — CN disclosed
CN-101229117-A Thermostatic sustained release injection containing phosphatidylinositol 3-genistein inhibitor and preparing method thereof SHANDONG LANJIN PHARMACEUTICAL (CN) 2008-07-30 — — CN disclosed
CN-101019828-A Anticancer composition containing both phosphoinositide-3-kinase inhibitor and hormone medicine JINAN SHUAIHUA MEDICINE SCI TE (CN) 2007-08-22 — — CN disclosed
CN-101019830-A Anticancer composition containing phosphoinositide 3-kinase inhibitor and topoisomerase inhibitor JINAN SHUAIHUA MEDICINE SCI TE (CN) 2007-08-22 — — CN disclosed
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS NASTECH PHARMACEUTICAL COMPANY INC. 2007-04-05 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070077283-A1 METHOD OF ENHANCING TRANSMUCOSAL DELIVERY OF THERAPEUTIC COMPOUNDS PGF, PLAT, PTAFR AKT1 2500/4885PRKD3 4274/4885PRKCG 1674/4885
US-20260005070-A1 DICING SYSTEM AND DICING METHOD CAD, DSG1, MATR3 AKT1 3547/4885PRKD3 3099/4885PRKCG 2621/4885
US-11529361-B2 Halogenated salicylanilides for treating Clostridium infections SLC10A2, FABP2, SI AKT1 3922/4885PRKD3 1515/4885PRKCG 3566/4885
US-20110144137-A1 METHOD FOR PREVENTING OR ALLEVIATING THE NOXIOUS EFFECTS RESULTING FROM TOXICANT EXPOSURE TRPA1, HRH2, HRH4 AKT1 3695/4885PRKD3 1941/4885PRKCG 288/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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