SCHEMBL12387555

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12387548	0.89	ALDH1A1 (0.37)	CYP1A2CYP3A4MAPTCYP2C9CYP2C19
	SCHEMBL12387536	0.86	KDM4E (0.33)	CYP1A2CYP3A4MAPTCYP2C9CYP2C19
	SCHEMBL12387538	0.86	KDM4E (0.33)	CYP1A2CYP3A4MAPTCYP2C9CYP2C19
	SCHEMBL30487699	0.83	ICMT (0.36)	ICMTLMNACYP1A2CYP3A4MAPT
	SCHEMBL14518387	0.83	ICMT (0.36)	ICMTLMNACYP1A2CYP3A4MAPT
	SCHEMBL31324815	0.83	ICMT (0.36)	ICMTLMNACYP1A2CYP3A4MAPT
	SCHEMBL12387535	0.83	ESR1 (0.32)	HTTL3MBTL1NPSR1
	SCHEMBL13304307	0.83	TDP1 (0.39)	LMNACYP1A2CYP3A4MAPTCYP2C9
	SCHEMBL13888822	0.83	HTT (0.32)	HTTL3MBTL1NPSR1
	SCHEMBL12387537	0.82	BACE1 (0.31)	CYP1A2CYP3A4MAPTCYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.