Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 10/20 | 0.38 |
| ▸ | HTR2B | P41595 | 5/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.30 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13586359 | 0.91 | CNR2 (0.39) | HTR2CHTR2BHTR2ACNR2FPR2 | |
| SCHEMBL12822967 | 0.91 | CNR2 (0.39) | HTR2CHTR2BHTR2ACNR2FPR2 | |
| SCHEMBL9920720 | 0.90 | HTR2C (0.36) | HTR2CHTR2BHTR2ACNR2RIPK1 | |
| SCHEMBL13762035 | 0.89 | HTR2C (0.36) | HTR2CHTR2BHTR2ACNR2RIPK1 | |
| SCHEMBL12388761 | 0.88 | HTR2C (0.35) | HTR2CHTR2BHTR2ARIPK1 | |
| SCHEMBL19160885 | 0.88 | GRIN1 (0.32) | — | |
| SCHEMBL24170503 | 0.87 | HTR2C (0.40) | HTR2CHTR2BHTR2ARIPK1PDE4B | |
| SCHEMBL14391042 | 0.87 | HTR2C (0.40) | HTR2CHTR2BHTR2ARIPK1PDE4B | |
| SCHEMBL10298113 | 0.86 | HTR2A (0.34) | HTR2CHTR2BHTR2A | |
| SCHEMBL13453184 | 0.86 | HTR2C (0.38) | HTR2CHTR2BHTR2ACNR2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120292569-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE USING THE SAME | DIC CORPORATION (JP) | 2012-11-22 | — | — | US | disclosed |
| US-8003006-B2 | Difluorobenzene derivative and nematic liquid crystal composition using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2011-08-23 | — | — | US | disclosed |
| US-7670504-B2 | Nematic liquid crystal composition and liquid crystal display device using the same | DAINIPPON INK & CHEMICALS, INC. (JP) | 2010-03-02 | — | — | US | disclosed |
| US-7651630-B2 | Difluorobenzene derivative and nematic liquid crystal composition using the same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20090200514-A1 | DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090050843-A1 | DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2009-02-26 | — | — | US | disclosed |
| US-20080111107-A1 | Nematic Liquid Crystal Composition And Liquid Crystal Display Device Using The Same | DAINIPPON INK AND CHEMICALS, INC. (JP) | 2008-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090050843-A1 | DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME | HCN2, TRPV2, TRPV5 | HTR2C 3149/4885HTR2B 3198/4885HTR2A 3728/4885 |
| US-20090200514-A1 | DIFLUOROBENZENE DERIVATIVE AND NEMATIC LIQUID CRYSTAL COMPOSITION USING THE SAME | TRPV2, HCN2, DVL1 | HTR2C 2621/4885HTR2B 2616/4885HTR2A 3375/4885 |
| US-20080111107-A1 | Nematic Liquid Crystal Composition And Liquid Crystal Display Device Using The Same | PIEZO1, KIF20B, VCL | HTR2C 2306/4885HTR2B 487/4885HTR2A 1878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.