Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 8/20 | 0.44 |
| ▸ | GABRD | O14764 | 8/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.44 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.44 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.44 |
| ▸ | GABRE | P78334 | 8/20 | 0.44 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.44 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.44 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.44 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.44 |
| ▸ | PIM1 | P11309 | 3/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.42 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.42 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504758 | 0.86 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL29902443 | 0.86 | GABRP (0.47) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25465859 | 0.85 | ALOX5 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30829289 | 0.85 | LOXL2 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3879946 | 0.85 | LOXL2 (0.41) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19346715 | 0.82 | TP53 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL25290758 | 0.82 | MAPT (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL21177655 | 0.82 | AHR (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL18820608 | 0.82 | PIM1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL24343633 | 0.82 | MAOA (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633316-B2 | Producing method of nitrogen containing condensed heterocyclic compound | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-8633316-B2 | Producing method of nitrogen containing condensed heterocyclic compound | KONICA MINOLTA HOLDINGS, INC. (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110184176-A1 | PRODUCING METHOD OF NITROGEN CONTAINING CONDENSED HETEROCYCLIC COMPOUND | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-07-28 | — | — | US | disclosed |
| US-20110184176-A1 | PRODUCING METHOD OF NITROGEN CONTAINING CONDENSED HETEROCYCLIC COMPOUND | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-07-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110184176-A1 | PRODUCING METHOD OF NITROGEN CONTAINING CONDENSED HETEROCYCLIC COMPOUND | C5, NISCH, CBR3 | GABRP 3569/4885GABRD 4149/4885GABRA1 4146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.