SCHEMBL21177655

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29572034	1.00	AHR (0.51)	AHRTTRPIM1CSNK2A2CSNK2B
	SCHEMBL22117396	0.86	AHR (0.51)	AHRTTRPIM1CSNK2A2CSNK2B
	SCHEMBL29976750	0.86	AHR (0.51)	AHRTTRPIM1CSNK2A2CSNK2B
	SCHEMBL23765075	0.83	AHR (0.50)	AHRPIM1CSNK2A2CSNK2BPIM3
	SCHEMBL25290758	0.83	MAPT (0.42)	PIM1CSNK2A2CSNK2BPIM3PIM2
	SCHEMBL12396554	0.82	GABRP (0.44)	PIM1CSNK2A2CSNK2BPIM3PIM2
	SCHEMBL2287518	0.82	AHR (0.64)	AHRTTRPIM1CSNK2A2CSNK2B
	SCHEMBL23299464	0.79	AHR (0.61)	AHRPIM1CSNK2A2CSNK2BPIM3
	SCHEMBL21368353	0.79	AHR (0.51)	AHRTTR
	SCHEMBL24343637	0.79	AHR (0.51)	AHRTTRPIM1CSNK2A2CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.