SCHEMBL1240

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6841	0.91	CYP1A2 (0.38)	CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
	SCHEMBL18597928	0.84	LMNA (0.41)	LMNARAB9AALDH1A1MAPTTSHR
	SCHEMBL18597994	0.83	LPAR1 (0.48)	CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
	SCHEMBL18597843	0.82	MMP12 (0.41)	CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
	SCHEMBL18597930	0.82	PTGER1 (0.54)	CYP1A2CYP3A4CYP2C9CYP2C19CYP2D6
	SCHEMBL1796	0.79	LPAR1 (0.49)	CYP2C9CYP2C19LPAR1LPAR2LPAR3
	SCHEMBL18597759	0.79	LPAR1 (0.42)	LPAR1LPAR2LPAR3CRHBPCRHR2
	SCHEMBL1458	0.79	MAOB (0.40)	CYP1A2CYP3A4CYP2C9CYP2C19LPAR1
	SCHEMBL18597777	0.78	ALDH1A1 (0.44)	CYP1A2CYP3A4CYP2C9CYP2C19LPAR1
	SCHEMBL18597925	0.78	LPAR1 (0.43)	LPAR1LPAR2LPAR3MMP13SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.