SCHEMBL1240686

SCHEMBL1240686

CCCCCCCCCCCCCCC/C=C/C=C/C=C/[C]=O

nearest known ligand 0.59

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.59
TSHR P16473 1/20 0.59
FASN P49327 1/20 0.52
FAAH O00519 7/20 0.47
TRPV1 Q8NER1 1/20 0.47
KDM4E B2RXH2 1/20 0.44
CNR1 P21554 2/20 0.41
CNR2 P34972 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13370196 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL1239783 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL9696421 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL19063519 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL18398897 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL18398895 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL17479081 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL11030145 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL3130547 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1
SCHEMBL1237969 1.00 ALDH1A1 (0.59) ALDH1A1TSHRFASNFAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020048596-A1 PREPARATION FOR THE TRANSPORT OF AN ACTIVE SUBSTANCE ACROSS BARRIERS IDEA AG (DE) 2002-04-25 US claimed
US-20240099976-A1 BLENDED FORMULATIONS SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2024-03-28 US disclosed
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID NIPPON SHOKUBAI CO., LTD. (JP) 2024-01-11 US disclosed
US-11547665-B2 Multiphasic compositions SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2023-01-10 US disclosed
EP-3954361-A1 MULTIPHASIC COMPOSITIONS Sequessome Technology Holdings Limited (MT) 2022-02-16 EP disclosed
US-20210393655-A1 Vesicular Formulations for Use in the Treatment of Pain or Reduced Mobility of a Joint SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2021-12-23 US disclosed
EP-3316857-B1 MULTIPHASIC COMPOSITIONS SEQUESSOME TECH HOLDINGS LIMITED (MT) 2021-08-04 EP disclosed
EP-3316856-B1 BLENDED FORMULATIONS SEQUESSOME TECH HOLDINGS LIMITED (MT) 2021-04-07 EP disclosed
US-20210023007-A1 BLENDED FORMULATIONS SEQUESSOME TECH HOLDINGS LIMITED (US) 2021-01-28 US disclosed
US-20210007989-A1 MULTIPHASIC COMPOSITIONS SEQUESSOME TECHNOLOGY HOLDINGS LIMITED (MT) 2021-01-14 US disclosed
US-7820720-B2 Topical terbinafine formulations and methods of administering same for the treatment of fungal infections TDT LIMITED (MT) 2010-10-26 US disclosed
WO-2010090654-A1 METHODS OF REDUCING THE PROLIFERATION AND VIABILITY OF MICROBIAL AGENTS TDT, LTD. (MT) 2010-08-12 WO disclosed
US-20100197621-A1 METHODS OF REDUCING THE PROLIFERATION AND VIABILITY OF MICROBIAL AGENTS TARGETED DELIVERY TECHNOLOGIES LIMITED (MT) 2010-08-05 US disclosed
US-20100104633-A1 antifungal formulations comprising terbinafine or a pharmaceutically acceptable salt thereof, a lipid, and a surfactant; uses thereof for the treatment of skin and nail fungal infections CEVC GREGOR 2010-04-29 US disclosed
US-20100086504-A1 METHODS OF ADMINISTERING TOPICAL ANTIFUNGAL FORMULATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS TDT LIMITED (MT) 2010-04-08 US disclosed
WO-2010010470-A2 METHODS OF ADMINISTERING TOPICAL ANTIFUNGAL FORMULATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS TDT, LTD (MT) 2010-01-28 WO disclosed
US-20020048596-A1 PREPARATION FOR THE TRANSPORT OF AN ACTIVE SUBSTANCE ACROSS BARRIERS IDEA AG (DE) 2002-04-25 US disclosed
EP-0708645-A1 USE OF COMPOUNDS WHICH INHIBIT PHOSPHATIDIC ACID FORMATION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER CELL THERAPEUTICS, INC. (US) 1996-05-01 EP disclosed
WO-1995024199-A2 USE OF COMPOUNDS WHICH INHIBIT PHOSPHATIDIC ACID FORMATION FOR THE MANUFACTURE OF A MEDICAMENT FOR THE TREATMENT OF CANCER CELL THERAPEUTICS, INC. (US) 1995-09-14 WO disclosed
EP-0503508-A1 Vesicles and polymeric vesicles Kao Corporation (JP) 1992-09-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240009092-A1 COSMETIC COMPOSITION AND COSMETIC QUASI-DRUG INCLUDING LIPID PARTICLES CONTAINING PHOSPHOLIPID PLIN5, PHOSPHO1, PLIN3 ALDH1A1 524/4885TSHR 1575/4885FASN 174/4885
US-20100104633-A1 antifungal formulations comprising terbinafine or a pharmaceutically acceptable salt thereof, a lipid, and a surfactant; uses thereof for the treatment of skin and nail fungal infections DPM1, PIK3C3, NACA ALDH1A1 3968/4885TSHR 3481/4885FASN 689/4885
US-20100086504-A1 METHODS OF ADMINISTERING TOPICAL ANTIFUNGAL FORMULATIONS FOR THE TREATMENT OF FUNGAL INFECTIONS DPM1, ERG28, NACA ALDH1A1 3533/4885TSHR 3546/4885FASN 289/4885
US-20100197621-A1 METHODS OF REDUCING THE PROLIFERATION AND VIABILITY OF MICROBIAL AGENTS MGLL, LIPA, LPO ALDH1A1 2166/4885TSHR 4213/4885FASN 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.