SCHEMBL1240957

SCHEMBL1240957

[CH2]CC(C)(C)NC(=O)CCCCCCCCCCC

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.61
HSP90AA1 P07900 1/20 0.52
FAAH O00519 6/20 0.50
HRH3 Q9Y5N1 1/20 0.49
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
MAPK1 P28482 1/20 0.47
CES2 O00748 3/20 0.43
CES1 P23141 3/20 0.43
LMNA P02545 1/20 0.43
POLB P06746 1/20 0.43
GRK2 P25098 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
TRPV1 Q8NER1 2/20 0.42
DNM1 Q05193 1/20 0.42
EPHX1 P07099 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28609299 1.00 ALDH1A1 (0.61) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL1176907 1.00 ALDH1A1 (0.61) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL2236831 1.00 ALDH1A1 (0.61) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL7633732 1.00 ALDH1A1 (0.61) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL5592299 0.85 ALDH1A1 (0.66) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL23392423 0.83 ALDH1A1 (0.63) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL19783828 0.83 ALDH1A1 (0.75) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL11922964 0.83 ALDH1A1 (0.63) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL28470106 0.83 ALDH1A1 (0.75) ALDH1A1HSP90AA1FAAHHRH3MEN1
SCHEMBL10689611 0.83 ALDH1A1 (0.63) ALDH1A1HSP90AA1FAAHHRH3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115317961-A Preparation method of dimethyl silicone oil defoaming agent 哈药集团技术中心 2022-11-11 CN claimed
CN-114524742-A Preparation method of high-purity lauramidopropyl betaine 山东大学 2022-05-24 CN disclosed
CN-111088002-B Acidity-sensitive shunt temporary plugging agent and preparation method and application thereof 中国石油天然气股份有限公司 2021-11-30 CN disclosed
CN-111088002-A Acidity-sensitive shunt temporary plugging agent and preparation method and application thereof 中国石油天然气股份有限公司 2020-05-01 CN disclosed
EP-2555747-B1 A COMBINATION OF CROSSLINKED CATIONIC POLYMER AND AMPHOLYTIC POLYMER FOR PERSONAL AND HOUSEHOLD APPLICATIONS LUBRIZOL ADVANCED MAT INC (US) 2017-02-22 EP disclosed
EP-1558202-B1 WATER SOLUBLE MONOMERS AND POLYMERS FOR PROTECTING SUBTRATES FROM ULTRAVIOLET LIGHT NALCO CO (US) 2016-11-16 EP disclosed
EP-1998744-B1 LOW MOLECULAR WEIGHT AMPHOLYTIC POLYMERS FOR PERSONAL CARE APPLICATIONS LUBRIZOL ADVANCED MAT INC (US) 2015-06-10 EP disclosed
US-9017652-B1 Combination of crosslinked cationic and ampholytic polymers for personal and household applications LUBRIZOL ADVANCED MATERIALS, INC. (US) 2015-04-28 US disclosed
US-8829118-B2 Method for using hydrophobically modified polymers in consumer and industrial applications NALCO COMPANY (US) 2014-09-09 US disclosed
US-8658145-B2 Low molecular weight ampholytic polymers for personal care applications THE LUBRIZOL CORPORATION (US) 2014-02-25 US disclosed
US-6887400-B1 Water-soluble polyaminoamides comprising 1,3-diimines as sunscreen agents NALCO COMPANY (US) 2005-05-03 US disclosed
US-20050064025-A1 Compositions and methods for treating, preventing and/or ameliorating cancers, the onset of cancers or the symptoms of cancers THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM 2005-03-24 US disclosed
WO-2005025491-A2 WATER-SOLUBLE POLYAMIOAMIDES AS SUNSCREEN AGENTS NALCO COMPANY (US) 2005-03-24 WO disclosed
WO-2004060273-A2 SKIN CARE COMPOSITION CONTAINING AN ANIONIC POLYMER NALCO COMPANY (US) 2004-07-22 WO disclosed
EP-1383462-A4 COSMETIC COMPOSITIONS CONTAINING DISPERSION POLYMERS ONDEO NALCO CO (US) 2004-07-07 EP disclosed
WO-2004043412-A1 WATER SOLUBLE MONOMERS AND POLYMERS FOR PROTECTING SUBTRATES FROM ULTRAVIOLET LIGHT NALCO COMPANY (US) 2004-05-27 WO disclosed
US-6696067-B2 FOR TREATING HAIR, SKIN OR NAILS, COMPRISES AN AQUEOUS SALT SOLUTION OF A CATIONIC, ANIONIC OR NONIONIC POLYMER OF GIVEN WEIGHT AVERAGE MOLECULAR WEIGHT, FOR EXAMPLE A COPOLYMER OF ACRYLAMIDE AND DIALLYLDIMETHYLAMMONIUM CHLORIDE ONDEO NALCO COMPANY 2004-02-24 US disclosed
EP-1383462-A1 COSMETIC COMPOSITIONS CONTAINING DISPERSION POLYMERS Ondeo Nalco Company (US) 2004-01-28 EP disclosed
US-20030059382-A1 Cosmetic compositions containing dispersion polymers ECOLAB USA INC. 2003-03-27 US disclosed
WO-2002083085-A1 COSMETIC COMPOSITIONS CONTAINING DISPERSION POLYMERS ONDEO NALCO COMPANY (US) 2002-10-24 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030059382-A1 Cosmetic compositions containing dispersion polymers POLR1C, NACA, TYR ALDH1A1 2279/4885HSP90AA1 2590/4885FAAH 3232/4885
US-20050064025-A1 Compositions and methods for treating, preventing and/or ameliorating cancers, the onset of cancers or the symptoms of cancers PTGES, ALOX5, PTGES3 ALDH1A1 1304/4885HSP90AA1 264/4885FAAH 549/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.