Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | SCN4A | P35499 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5123894 | 1.00 | SIGMAR1 (0.51) | SIGMAR1L3MBTL1DRD2DRD4SCN4A | |
| SCHEMBL1724899 | 0.91 | DPP4 (0.48) | SIGMAR1L3MBTL1DRD2DRD4DPP4 | |
| SCHEMBL5924067 | 0.91 | DPP4 (0.48) | SIGMAR1L3MBTL1DRD2DRD4DPP4 | |
| SCHEMBL19972280 | 0.81 | MCHR1 (0.56) | SIGMAR1DRD2DRD4SCN4AMCHR1 | |
| SCHEMBL2934742 | 0.80 | DPP4 (0.67) | DPP4 | |
| SCHEMBL2934740 | 0.80 | DPP4 (0.67) | DPP4 | |
| SCHEMBL2934745 | 0.80 | DPP4 (0.67) | DPP4 | |
| SCHEMBL470519 | 0.77 | DPP4 (0.48) | SIGMAR1DRD2DPP4 | |
| SCHEMBL20597239 | 0.77 | SCN4A (0.56) | SIGMAR1L3MBTL1DRD2DRD4SCN4A | |
| SCHEMBL20597490 | 0.77 | SCN4A (0.56) | SIGMAR1L3MBTL1DRD2DRD4SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884104-B2 | Such as (3R,4R)-1-Pyrimidin-4-yl-4-(2,4,5-trifluorophenyl)piperidin-3-amine bis-trifluoroacetic acid salt | MERCK SHARP & DOHME CORP. (US) | 2011-02-08 | — | — | US | disclosed |