Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 6/20 | 0.56 |
| ▸ | FPR1 | P21462 | 5/20 | 0.56 |
| ▸ | FPR2 | P25090 | 2/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19972380 | 0.83 | SIGMAR1 (0.57) | MCHR1SIGMAR1DRD2DRD4 | |
| SCHEMBL19972364 | 0.81 | FPR1 (0.58) | FPR1FPR2 | |
| SCHEMBL1240975 | 0.81 | SIGMAR1 (0.51) | MCHR1SIGMAR1DRD2DRD4SCN4A | |
| SCHEMBL5123894 | 0.81 | SIGMAR1 (0.51) | MCHR1SIGMAR1DRD2DRD4SCN4A | |
| SCHEMBL19972293 | 0.79 | FPR1 (0.69) | FPR1FPR2 | |
| SCHEMBL19985856 | 0.78 | L3MBTL1 (0.45) | MCHR1FPR1FPR2SIGMAR1DRD2 | |
| SCHEMBL16032662 | 0.76 | SIGMAR1 (0.52) | MCHR1FPR2SIGMAR1DRD2 | |
| SCHEMBL16032661 | 0.76 | SIGMAR1 (0.52) | MCHR1FPR2SIGMAR1DRD2 | |
| SCHEMBL16032659 | 0.76 | SIGMAR1 (0.52) | MCHR1FPR2SIGMAR1DRD2 | |
| SCHEMBL19972292 | 0.75 | FPR1 (0.58) | FPR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3515902-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2019-07-31 | — | — | EP | disclosed |
| US-10265310-B2 | 6-membered cyclic amines or lactames substituted with urea and phenyl | Grünenthal GmbH (DE) | 2019-04-23 | — | — | US | disclosed |
| WO-2018054549-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-29 | — | — | WO | disclosed |
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | Grünenthal GmbH (DE) | 2018-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180078541-A1 | 6-MEMBERED CYCLIC AMINES OR LACTAMES SUBSTITUTED WITH UREA AND PHENYL | FPR2, FPR1, FPR3 | MCHR1 1889/4885FPR1 2/4885FPR2 1/4885 |
| US-10265310-B2 | 6-membered cyclic amines or lactames substituted with urea and phenyl | FPR2, FPR1, FPR3 | MCHR1 1889/4885FPR1 2/4885FPR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.