SCHEMBL139044

SCHEMBL139044

COc1cc(OC)cc(C(O)C(=O)c2ccccc2)c1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.59
CES1 P23141 3/20 0.59
LMNA P02545 2/20 0.59
NPC1 O15118 4/20 0.51
RAB9A P51151 4/20 0.51
HTT P42858 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MEN1 O00255 4/20 0.49
KMT2A Q03164 4/20 0.49
MAPT P10636 2/20 0.49
POLB P06746 1/20 0.49
ALDH1A1 P00352 2/20 0.47
KDM4E B2RXH2 1/20 0.47
L3MBTL1 Q9Y468 2/20 0.45
GAA P10253 1/20 0.44
PAX8 Q06710 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
RXRA P19793 1/20 0.44
TACR1 P25103 1/20 0.43
CASP3 P42574 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL291493 0.98 CES2 (0.58) CES2CES1LMNANPC1RAB9A
Acetic Acid SCHEMBL3368380 0.97 CES2 (0.56) CES2CES1LMNANPC1RAB9A
SCHEMBL28343389 0.95 CES2 (0.54) CES2CES1LMNANPC1RAB9A
Carbamic Acid SCHEMBL1695357 0.95 CES2 (0.54) CES2CES1LMNANPC1RAB9A
Phosphoric Acid SCHEMBL9151566 0.94 CES2 (0.53) CES2CES1LMNANPC1RAB9A
Acrylic Acid SCHEMBL10353178 0.91 CES2 (0.50) CES2CES1LMNANPC1RAB9A
SCHEMBL3364576 0.89 CES2 (0.47) CES2CES1LMNANPC1RAB9A
SCHEMBL8622126 0.87 CES2 (0.61) CES2CES1LMNANPC1RAB9A
SCHEMBL139043 0.87 LMNA (0.59) CES2CES1LMNANPC1RAB9A
SCHEMBL14181968 0.86 CES2 (0.48) CES2CES1MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 349 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2300067-B1 DRUG DELIVERY COMPOSITION THE QUEEN'S UNIV OF BELFAST (GB) 2017-10-25 EP claimed
US-9714560-B2 Protected scale inhibitors and methods relating thereto HALLIBURTON ENERGY SERVICES, INC. (US) 2017-07-25 US claimed
EP-2727915-B1 Synthesis of deuterated catechols and benzo[d][1,3]dioxoles and derivatives thereof CONCERT PHARMACEUTICALS INC (US) 2016-04-13 EP claimed
US-20110165114-A1 DRUG DELIVERY COMPOSITION QUEEN'S UNIVERSITY OF BELFAST, THE (GB) 2011-07-07 US claimed
EP-2300067-A2 DRUG DELIVERY COMPOSITION The Queen's University of Belfast (GB) 2011-03-30 EP claimed
WO-2009147372-A2 DRUG DELIVERY COMPOSITION THE QUEEN'S UNIVERSITY OF BELFAST (GB) 2009-12-10 WO claimed
EP-1401851-B8 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT HOLDING GMBH (DE) 2008-09-10 EP claimed
EP-1401851-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS Febit AG (DE) 2004-03-31 EP claimed
WO-2003004510-A1 TWO-STAGE PROTECTIVE GROUPS FOR THE SYNTHESIS OF BIOPOLYMERS FEBIT AG (DE) 2003-01-16 WO claimed
EP-0123159-B1 POSITIVE-WORKING PHOTOSENSITIVE BENZOIN ESTERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-09-05 EP claimed
WO-2026090073-A1 POLYMERIC PARTICLES FOR PROXIMITY-BASED CELLULAR DNA-ENCODED LIBRARY SCREENING AND METHODS OF USE GENENTECH, INC. (US) 2026-04-30 WO disclosed
EP-3434764-B1 FABRIC AND HOME CARE PRODUCTS PROCTER & GAMBLE (US) 2026-04-08 EP disclosed
US-20250344929-A1 Fibrous Structures Comprising Particles and Methods for Making Same PROCTER & GAMBLE (US) 2025-11-13 US disclosed
EP-4197598-B1 ACTIVE AGENT-CONTAINING ARTICLES THAT EXHIBIT CONSUMER ACCEPTABLE ARTICLE IN-USE PROPERTIES PROCTER & GAMBLE (US) 2025-10-22 EP disclosed
US-12440083-B2 Fibrous structures comprising particles and methods for making same THE PROCTER & GAMBLE COMPANY (US) 2025-10-14 US disclosed
EP-0046083-B1 PHOTOLABILE BLOCKED SURFACTANTS AND COMPOSITIONS CONTAINING THE SAME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-16 EP disclosed
EP-0123159-A2 Positive-working photosensitive benzoin esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-10-31 EP disclosed
US-4478967-A Photolabile blocked surfactants and compositions containing the same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1984-10-23 US disclosed
US-4469774-A RELIEF PRINTING PLATES, PHOTORESISTS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1984-09-04 US disclosed
EP-0046083-A2 Photolabile blocked surfactants and compositions containing the same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1982-02-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110165114-A1 DRUG DELIVERY COMPOSITION ECPAS, ABCB11, ABCB1 CES2 427/4885CES1 714/4885LMNA 135/4885
US-12440083-B2 Fibrous structures comprising particles and methods for making same FGB, CD68, SDCBP CES2 2307/4885CES1 2200/4885LMNA 166/4885
US-20250344929-A1 Fibrous Structures Comprising Particles and Methods for Making Same FGB, CD68, SDCBP CES2 2307/4885CES1 2200/4885LMNA 166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.