SCHEMBL12412978

SCHEMBL12412978

Cc1ccc2c3sc4c5cc6sc7c(sc8c9ccc(C)cc9n(C)c87)c6cc5sc4c3n(C)c2c1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 4/20 0.33
MAPT P10636 2/20 0.33
MCL1 Q07820 2/20 0.33
KDM4E B2RXH2 1/20 0.33
APAF1 O14727 1/20 0.33
IDO1 P14902 1/20 0.33
MAPK1 P28482 1/20 0.33
HTT P42858 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
SRC P12931 1/20 0.33
RXFP1 Q9HBX9 1/20 0.32
MAOA P21397 1/20 0.31
DYRK1A Q13627 1/20 0.31
PARP15 Q460N3 2/20 0.31
PARP10 Q53GL7 2/20 0.31
TNKS2 Q9H2K2 2/20 0.31
PARP2 Q9UGN5 2/20 0.31
TNKS O95271 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12413189 0.89 PKM (0.35) PKMMAPTMCL1KDM4EAPAF1
SCHEMBL12412959 0.89 PKM (0.37) PKMMAPTMCL1KDM4EAPAF1
SCHEMBL12413018 0.87
SCHEMBL17281047 0.86 MCL1 (0.36) PKMMAPTMCL1KDM4EAPAF1
SCHEMBL12413057 0.84 MCL1 (0.33) PKMMAPTMCL1KDM4EAPAF1
SCHEMBL12412973 0.81 USP14 (0.33) HTT
SCHEMBL12413187 0.81 MCL1 (0.37) PKMMAPTMCL1KDM4EAPAF1
SCHEMBL12412960 0.79 MCL1 (0.38) PKMMAPTMCL1KDM4EAPAF1
SCHEMBL17281048 0.79 TP53 (0.43) MAPTKDM4ERAB9ATDP1SRC
SCHEMBL12412887 0.78 USP14 (0.31) MCL1HTTPARP15PARP10TNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SCLY, MSRB3, SOD1 PKM 4352/4885MAPT 4576/4885MCL1 4068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.