SCHEMBL12413119

SCHEMBL12413119

Cc1ccc(-n2c3cc(F)ccc3c3oc4cc5c(cc4c32)oc2c3ccc(F)cc3n(-c3ccc(C)cc3)c52)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 2/20 0.41
KAT2B Q92831 1/20 0.37
HTT P42858 3/20 0.34
MAT2A P31153 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
PIK3CD O00329 1/20 0.34
PIK3CA P42336 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
PPARG P37231 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
RXFP1 Q9HBX9 2/20 0.33
NR2E3 Q9Y5X4 2/20 0.33
NCOR2 Q9Y618 2/20 0.33
TSHR P16473 1/20 0.33
POLB P06746 1/20 0.33
NPBWR1 P48145 3/20 0.33
MCHR1 Q99705 3/20 0.33
MEN1 O00255 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12412942 0.89 ALDH1A1 (0.36) MAOBHTTKDM4EALDH1A1SMN1; SMN2
SCHEMBL12413175 0.85 MAOB (0.36) MAOBHTTKDM4EALDH1A1PIK3CD
SCHEMBL12413034 0.84 MAOB (0.35) MAOBHTTKDM4EALDH1A1PPARG
SCHEMBL12413145 0.83 HTT (0.33) HTTKDM4EALDH1A1SMN1; SMN2PPARG
SCHEMBL12412943 0.80 MAOB (0.39) MAOBHTTKDM4EALDH1A1SMN1; SMN2
SCHEMBL12413047 0.80 MAOB (0.33) MAOBHTTKDM4EALDH1A1PPARG
SCHEMBL12412992 0.80 ALDH1A1 (0.34) MAOBHTTKDM4EALDH1A1SMN1; SMN2
SCHEMBL12503795 0.79 HTT (0.39) MAOBHTTKDM4EALDH1A1SMN1; SMN2
SCHEMBL12413059 0.77 THRB (0.32) MAOBHTTKDM4EALDH1A1PPARG
SCHEMBL12412940 0.77 KDM4E (0.30) HTTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-07 US disclosed
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110166362-A1 NOVEL COMPOUND AND ORGANIC SEMICONDUCTOR MATERIAL SCLY, MSRB3, SOD1 MAOB 180/4885KAT2B 530/4885HTT 4130/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.