Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TRPC5 | Q9UL62 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12412024 | 0.93 | NPC1 (0.52) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL12412025 | 0.89 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL14641676 | 0.88 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL12412028 | 0.88 | NPC1 (0.63) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL12377299 | 0.86 | MAPT (0.53) | KMT2AALOX15CNR2TRPC5LMNA | |
| SCHEMBL12413900 | 0.81 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL12377324 | 0.80 | MAPT (0.52) | KMT2AALOX15TRPC5LMNATP53 | |
| SCHEMBL5226399 | 0.80 | RAB9A (0.57) | NPC1RAB9ASMN1; SMN2KMT2AMAPK1 | |
| SCHEMBL14521451 | 0.77 | TRPC5 (0.50) | SMN1; SMN2MAPK1CNR2TRPC5TP53 | |
| SCHEMBL12377300 | 0.76 | MRGPRX1 (0.46) | KMT2ATRPC5LMNAGAAAPP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7989422-B2 | Antibacterial agents | ALCHEMIA LIMITED (AU) | 2011-08-02 | — | — | US | disclosed |
| US-20090023669-A1 | Antibacterial Agents | ALCHEMIA LIMITED (AU) | 2009-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090023669-A1 | Antibacterial Agents | MRPL21, FUT6, FUT5 | NPC1 1617/4885RAB9A 1604/4885SMN1; SMN2 4524/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.