SCHEMBL12414523

SCHEMBL12414523

c1ccc2c(c1)sc1c(N(c3ccc(-c4ccc(N(c5cccc6c5sc5ccccc56)c5cccc6c5sc5ccccc56)cc4)cc3)c3cccc4c3sc3ccccc34)cccc12

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.44
GPR3 P46089 1/20 0.42
PARP14 Q460N5 1/20 0.35
TNKS O95271 3/20 0.35
TNKS2 Q9H2K2 3/20 0.35
PTPN1 P18031 2/20 0.35
MAPT P10636 4/20 0.34
RAB9A P51151 4/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
ALDH1A1 P00352 3/20 0.34
L3MBTL1 Q9Y468 2/20 0.34
ATM Q13315 1/20 0.34
KDM4E B2RXH2 1/20 0.34
HPGD P15428 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
APP P05067 1/20 0.32
LIMK1 P53667 1/20 0.32
CDK5 Q00535 1/20 0.32
CDK5R1 Q15078 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15964352 0.97 ALOX5 (0.42) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL15964350 0.97 ALOX5 (0.42) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL12414528 0.95 ALOX5 (0.41) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL12414522 0.95 ALOX5 (0.41) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL12414530 0.94 ALOX5 (0.40) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL12414526 0.94 ALOX5 (0.40) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL17126441 0.94 ALOX5 (0.42) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL15964514 0.94 ALOX5 (0.42) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL14295385 0.94 ALOX5 (0.42) ALOX5GPR3PARP14TNKSTNKS2
SCHEMBL29430067 0.94 ALOX5 (0.42) ALOX5GPR3PARP14TNKSTNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185333-B1 ORGANOSELENIUM MATERIALS AND THEIR USES IN ORGANIC LIGHT EMITTING DEVICES UNIVERSAL DISPLAY CORP (US) 2023-09-06 EP disclosed
US-10276637-B2 Organic EL multi-color light-emitting device IDEMITSU KOSAN CO., LTD. (JP) 2019-04-30 US disclosed
EP-2628778-B1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORP (US) 2016-03-16 EP disclosed
US-20140159023-A1 ORGANIC EL MULTI-COLOR LIGHT-EMITTING DEVICE Idemitsu Co., Ltd. (JP) 2014-06-12 US disclosed
US-20140159023-A1 ORGANIC EL MULTI-COLOR LIGHT-EMITTING DEVICE Idemitsu Co., Ltd. (JP) 2014-06-12 US disclosed
US-8652653-B2 Hole transport materials having a sulfur-containing group UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 US disclosed
US-8652653-B2 Hole transport materials having a sulfur-containing group UNIVERSAL DISPLAY CORPORATION (US) 2014-02-18 US disclosed
EP-2628778-A1 Hole transport materials having a sulfur-containing group Universal Display Corporation (US) 2013-08-21 EP disclosed
EP-2321376-B1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORP (US) 2013-06-19 EP disclosed
US-20120319091-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-12-20 US disclosed
US-20120319091-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-12-20 US disclosed
US-20110163302-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2011-07-07 US disclosed
US-20110163302-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2011-07-07 US disclosed
WO-2010002848-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP UNIVERSAL DISPLAY CORPORATION (US) 2010-01-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110163302-A1 HOLE TRANSPORT MATERIALS HAVING A SULFUR-CONTAINING GROUP TST, SLC43A1, SLC6A4 ALOX5 3112/4885GPR3 3600/4885PARP14 2510/4885
US-20120319091-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME INMT, TYR, ALKBH2 ALOX5 1298/4885GPR3 3415/4885PARP14 2182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.