Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16841331 | 1.00 | ALOX5 (0.33) | ALOX5HTR2A | |
| SCHEMBL22292429 | 0.83 | ALOX5 (0.33) | ALOX5 | |
| SCHEMBL22292454 | 0.81 | — | — | |
| SCHEMBL13946976 | 0.79 | MAPT (0.44) | — | |
| SCHEMBL20852649 | 0.78 | — | — | |
| SCHEMBL19347357 | 0.76 | ALDH1A1 (0.39) | HTR2A | |
| SCHEMBL12394799 | 0.75 | ALOX5 (0.35) | ALOX5 | |
| SCHEMBL13723082 | 0.73 | PTGS1 (0.36) | — | |
| SCHEMBL13026632 | 0.73 | CYP2E1 (0.39) | ALOX5HTR2A | |
| SCHEMBL9906043 | 0.72 | SMN1; SMN2 (0.50) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172299-A1 | THERAPEUTIC SUBSTITUTED CYCLOPENTANES | ALLERGAN, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-20110172299-A1 | THERAPEUTIC SUBSTITUTED CYCLOPENTANES | ALLERGAN, INC. (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172299-A1 | THERAPEUTIC SUBSTITUTED CYCLOPENTANES | TUBB6, TUBB3, TUBB2A | ALOX5 36/4885HTR2A 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.