Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 12/20 | 0.60 |
| ▸ | MAOA | P21397 | 5/20 | 0.55 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.53 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.51 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2198299 | 0.99 | MAOB (0.59) | MAOBMAOAHTR6PRMT5SIGMAR1 | |
| SCHEMBL21347499 | 0.88 | HRH3 (0.66) | MAOBMAOAHRH3 | |
| SCHEMBL2233922 | 0.85 | HRH3 (0.64) | MAOBSIGMAR1HRH3NPC1TP53 | |
| SCHEMBL14859644 | 0.84 | SIGMAR1 (0.70) | PRMT5SIGMAR1HRH3NPC1TP53 | |
| SCHEMBL608181 | 0.83 | ALDH1A1 (0.70) | SIGMAR1 | |
| SCHEMBL29566534 | 0.83 | ALDH1A1 (0.70) | SIGMAR1 | |
| SCHEMBL2193907 | 0.83 | MAOB (0.56) | MAOBMAOAHTR6PRMT5NR4A2 | |
| Hydrochloric Acid SCHEMBL2924548 | 0.82 | ALDH1A1 (0.68) | SIGMAR1 | |
| Hydrochloric Acid SCHEMBL7426019 | 0.82 | ALDH1A1 (0.68) | SIGMAR1 | |
| SCHEMBL12420762 | 0.81 | NR4A2 (0.55) | MAOBMAOAPRMT5NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | MAOB 222/4885MAOA 309/4885HTR6 3435/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.