Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | CASP2 | P42575 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.35 |
| ▸ | FNTA | P49354 | 2/20 | 0.35 |
| ▸ | FNTB | P49356 | 2/20 | 0.35 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12417550 | 0.94 | TSHR (0.47) | ALDH1A1TSHRFAAHLPAR1CASP2 | |
| SCHEMBL13225553 | 0.90 | ALDH1A1 (0.58) | ALDH1A1TSHRFAAHLPAR1CASP2 | |
| SCHEMBL13339624 | 0.86 | TSHR (0.41) | ALDH1A1TSHRFAAHLPAR1CASP2 | |
| SCHEMBL10036633 | 0.82 | ALDH1A1 (0.62) | ALDH1A1TSHRFAAHLPAR1CASP2 | |
| SCHEMBL12107776 | 0.81 | ALDH1A1 (0.52) | ALDH1A1FAAHLPAR1CASP2HPGD | |
| SCHEMBL10025175 | 0.81 | CASP2 (0.52) | ALDH1A1FAAHLPAR1CASP2HPGD | |
| SCHEMBL12417380 | 0.81 | LPAR1 (0.40) | ALDH1A1FAAHLPAR1HPGDMAPT | |
| SCHEMBL16015493 | 0.81 | SLC6A5 (0.50) | ALDH1A1FAAHLPAR1SMN1; SMN2DNM1 | |
| SCHEMBL18082922 | 0.80 | TSHR (0.37) | ALDH1A1TSHRFAAHLPAR1CASP2 | |
| SCHEMBL14477579 | 0.80 | DNM1 (0.40) | ALDH1A1FAAHLPAR1CASP2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8636994-B2 | Polymer-based compositions and conjugates of antimicrobial agents | NEKTAR THERAPEUTICS (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130195839-A1 | Polymer-Based Compositions and Conjugates of Antimicrobial Agents | NAKTAR THERAPEUTICS (US) | 2013-08-01 | — | — | US | disclosed |
| US-20110171165-A1 | POLYMER CONJUGATES OF OPIOID GROWTH FACTOR PEPTIDES | NEKTAR THERAPEUTICS | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130195839-A1 | Polymer-Based Compositions and Conjugates of Antimicrobial Agents | DDOST, CLSPN, DAD1 | ALDH1A1 3889/4885TSHR 4618/4885FAAH 4531/4885 |
| US-20110171165-A1 | POLYMER CONJUGATES OF OPIOID GROWTH FACTOR PEPTIDES | OGFR, OGFRL1, OPRL1 | ALDH1A1 2260/4885TSHR 1303/4885FAAH 1874/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.