Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 1/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
| ▸ | TGM2 | P21980 | 2/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL277624 | 0.92 | SIRT2 (0.38) | ACESIRT2SIRT1HDAC4TGM2 | |
| SCHEMBL12692567 | 0.91 | SIRT2 (0.41) | SIRT2SIRT1HDAC4HDAC3HDAC1 | |
| SCHEMBL12213104 | 0.91 | MEN1 (0.41) | SIRT2SIRT1TGM2KMT2A | |
| SCHEMBL13167106 | 0.90 | ACE (0.36) | ACESIRT2SIRT1HDAC4HDAC3 | |
| SCHEMBL13339221 | 0.89 | SIRT2 (0.35) | ACESIRT2SIRT1HDAC4HDAC3 | |
| SCHEMBL24064905 | 0.87 | SIRT1 (0.36) | SIRT2SIRT1TGM2KMT2ABRD4 | |
| SCHEMBL22357159 | 0.87 | MEN1 (0.35) | SIRT2SIRT1TGM2KMT2AFOLH1 | |
| SCHEMBL21202320 | 0.86 | NPY4R (0.39) | SIRT1TGM2KMT2A | |
| SCHEMBL21284264 | 0.85 | TGM2 (0.35) | SIRT1TGM2KMT2A | |
| SCHEMBL30804479 | 0.83 | TAS1R3 (0.40) | HDAC2KMT2APOLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110171160-A1 | POLYMER CONJUGATES OF KISS1 PEPTIDES | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110171160-A1 | POLYMER CONJUGATES OF KISS1 PEPTIDES | KISS1R, PROKR1, NGLY1 | ACE 2877/4885SIRT2 1016/4885SIRT1 473/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.