SCHEMBL12424868

SCHEMBL12424868

O=C1NC(c2ccc(F)c(F)c2)=C2C(=O)NC(c3ccc(F)c(F)c3)=C12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.39
GRM5 P41594 1/20 0.39
PRF1 P14222 1/20 0.38
PGR P06401 5/20 0.38
PTGS2 P35354 3/20 0.36
PTGS1 P23219 2/20 0.36
TDP2 O95551 1/20 0.36
IDO1 P14902 1/20 0.36
MAOB P27338 1/20 0.35
DAPK3 O43293 1/20 0.35
NTRK1 P04629 1/20 0.35
PIM1 P11309 1/20 0.35
FLT3 P36888 1/20 0.35
GSK3B P49841 1/20 0.35
ROCK1 Q13464 1/20 0.35
CLK4 Q9HAZ1 1/20 0.35
PDE3B Q13370 1/20 0.35
PDE3A Q14432 1/20 0.35
CREBBP Q92793 1/20 0.35
TYMP P19971 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12425046 0.93 PRF1 (0.35) NOTUMGRM5PRF1PGRPTGS2
SCHEMBL12424888 0.85 TDP2 (0.51) PGRPTGS2PTGS1TDP2CREBBP
SCHEMBL12424939 0.83 PARP1 (0.41) TDP2DAPK3NTRK1PIM1FLT3
SCHEMBL12424859 0.79 CES2 (0.33) PTGS2
SCHEMBL12424993 0.78 MAPT (0.37) GRM5PGRTDP2PDE3BPDE3A
SCHEMBL12424865 0.77 MAPT (0.41) NOTUMGRM5PTGS1PIM1TYMP
SCHEMBL18049419 0.76 PTGS2 (0.60) GRM5PTGS2GSK3B
SCHEMBL12424864 0.74 NOTUM (0.44) NOTUMGRM5PRF1PGRIDO1
SCHEMBL12424860 0.74 PTGS2 (0.44) PTGS2TDP2MAOBGSK3B
SCHEMBL18049411 0.74 PTGS2 (0.54) GRM5PTGS2GSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed