SCHEMBL12424876

SCHEMBL12424876

Cc1ccc(F)cc1C1=C2C(=O)NC(c3cc(F)ccc3C)=C2C(=O)N1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
FLT3 P36888 2/20 0.39
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
PDGFRB P09619 1/20 0.38
PARP1 P09874 1/20 0.38
PARP10 Q53GL7 1/20 0.38
CASP3 P42574 1/20 0.36
TGM2 P21980 1/20 0.36
STK10 O94804 1/20 0.35
SLK Q9H2G2 1/20 0.35
ABL1 P00519 4/20 0.35
FABP6 P51161 1/20 0.35
SLC9A1 P19634 1/20 0.35
ACHE P22303 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424872 0.81 CA9 (0.40) MEN1KMT2AFLT3CA1CA2
SCHEMBL12424938 0.79 CA1 (0.38) MEN1KMT2ACA1CA2CA7
SCHEMBL12424879 0.78 STK10 (0.50) PDGFRBSTK10SLKSLC9A1
SCHEMBL12424871 0.78 TDP2 (0.46) MEN1KMT2AFLT3CA1CA2
SCHEMBL12424889 0.75 STK10 (0.43) NISCHMEN1KMT2ACA1CA2
SCHEMBL30377758 0.73 NISCH (0.52) NISCHCA1CA2CA7CA9
SCHEMBL9139591 0.73 NISCH (0.52) NISCHCA1CA2CA7CA9
SCHEMBL2301106 0.73 DAO (0.46) PARP1PARP10CASP3
SCHEMBL12424869 0.71 NISCH (0.41) NISCHFLT3CA1CA2CA7
SCHEMBL12424741 0.70 GAA (0.49) MEN1KMT2ACA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed