SCHEMBL12424889

SCHEMBL12424889

O=C1NC(c2ccc(F)cc2Cl)=C2C(=O)NC(c3ccc(F)cc3Cl)=C12

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STK10 O94804 2/20 0.43
SLK Q9H2G2 2/20 0.43
NISCH Q9Y2I1 1/20 0.41
PRKCB P05771 2/20 0.40
PRKCA P17252 2/20 0.40
GSK3B P49841 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
PDE3B Q13370 1/20 0.37
PDE3A Q14432 1/20 0.37
TDP2 O95551 2/20 0.37
SIRT2 Q8IXJ6 1/20 0.37
GRM5 P41594 2/20 0.37
AKR1A1 P14550 1/20 0.37
AKR1B1 P15121 1/20 0.37
HSD11B1 P28845 1/20 0.36
PPOX P50336 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424908 0.81 PPOX (0.52) STK10SLKGSK3BAKR1A1AKR1B1
SCHEMBL12424871 0.81 TDP2 (0.46) PRKCBPRKCACA1CA2CA7
SCHEMBL12424872 0.78 CA9 (0.40) PRKCBPRKCACA1CA2CA7
SCHEMBL12424876 0.75 NISCH (0.41) STK10SLKNISCHCA1CA2
SCHEMBL12424938 0.75 CA1 (0.38) STK10SLKPRKCBPRKCACA1
SCHEMBL12424899 0.75 CDK4 (0.46) STK10SLKPRKCAGSK3BCA1
SCHEMBL9340330 0.73 STK10 (0.57) STK10SLKPRKCAGSK3B
SCHEMBL12424887 0.73 PPOX (0.50) GSK3BTDP2PPOXTGM2MAPT
SCHEMBL12424890 0.71 CES1 (0.44) STK10SLKPRKCAGSK3BTGM2
SCHEMBL12424879 0.71 STK10 (0.50) STK10SLKGSK3B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed