SCHEMBL12424869

SCHEMBL12424869

Cc1ccc(F)c(C2=C3C(=O)NC(c4cc(C)ccc4F)=C3C(=O)N2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NISCH Q9Y2I1 1/20 0.41
ROS1 P08922 1/20 0.41
CDK5 Q00535 1/20 0.41
ACVR1 Q04771 1/20 0.41
LRRK2 Q5S007 1/20 0.41
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA4 P22748 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
PARP10 Q53GL7 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
PARP1 P09874 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
ELANE P08246 1/20 0.36
CSNK1G1 Q9HCP0 1/20 0.36
GSK3B P49841 2/20 0.36
DAPK3 O43293 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23954121 0.92 ROS1 (0.43) NISCHROS1CDK5ACVR1LRRK2
SCHEMBL12425004 0.88 CES1 (0.35) NISCHROS1CDK5ACVR1LRRK2
SCHEMBL12424877 0.88 HSD17B10 (0.40) NISCHROS1CDK5ACVR1LRRK2
SCHEMBL12425008 0.85 STK10 (0.44) ROS1CDK5ACVR1LRRK2ELANE
SCHEMBL12424872 0.81 CA9 (0.40) LRRK2CA1CA2CA4CA7
SCHEMBL12424887 0.80 PPOX (0.50) CDK5ACVR1LRRK2PARP10PARP1
SCHEMBL12424972 0.80 TGM2 (0.46) CDK5LRRK2TDP1GSK3BDAPK3
SCHEMBL12425003 0.80 PTGS2 (0.42) NISCHBRD4
SCHEMBL12424878 0.78 ALDH1A1 (0.44) LRRK2TDP1PIM1ALDH1A1LMNA
SCHEMBL12424741 0.78 GAA (0.49) ROS1CDK5ACVR1LRRK2CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230050869-A1 THERMOELECTRIC CONVERSION MATERIAL, AND THERMOELECTRIC CONVERSION ELEMENT PREPARED THEREWITH TOYO INK SC HOLDINGS CO., LTD. (JP) 2023-02-16 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed