SCHEMBL12424902

SCHEMBL12424902

CCc1ccc(C2=C3C(=O)NC(c4cc(Cl)ccc4F)=C3C(=O)N2)c(F)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPOX P50336 1/20 0.40
MAPT P10636 4/20 0.34
CES1 P23141 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 2/20 0.34
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPK1 P28482 1/20 0.34
RAB9A P51151 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
TGM2 P21980 1/20 0.34
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
CBX7 O95931 1/20 0.33
CDYL2 Q8N8U2 1/20 0.33
CDYL Q9Y232 1/20 0.33
CDY1; CDY1B Q9Y6F8 1/20 0.33
KDM4E B2RXH2 1/20 0.33
LRRK2 Q5S007 1/20 0.33
S100A4 P26447 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424887 0.83 PPOX (0.50) PPOXMAPTCES1LMNATGM2
SCHEMBL12424877 0.80 HSD17B10 (0.40) MAPTSMN1; SMN2LMNANPC1ALDH1A1
SCHEMBL12424869 0.70 NISCH (0.41) MAPTLMNAALDH1A1L3MBTL1MAOA
SCHEMBL13761383 0.70 GRM2 (0.45) MAPTSMN1; SMN2LMNANPC1ALDH1A1
SCHEMBL12424882 0.70 PPOX (0.48) PPOXMAPTCES1SMN1; SMN2LMNA
SCHEMBL12424872 0.69 CA9 (0.40) MAPTCES1TGM2KDM4ELRRK2
SCHEMBL12424871 0.69 TDP2 (0.46) MAPTLMNAALDH1A1TGM2KDM4E
SCHEMBL12424908 0.69 PPOX (0.52) PPOXMAPTCES1SMN1; SMN2LMNA
SCHEMBL12424906 0.69 PPOX (0.52) PPOXMAPTCES1ALDH1A1TGM2
SCHEMBL22625805 0.69 CDK2 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed