SCHEMBL12424914

SCHEMBL12424914

O=C1NC(c2cc(F)c(F)c(F)c2F)=C2C(=O)NC(c3cc(F)c(F)c(F)c3F)=C12

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 1/20 0.32
GRM5 P41594 1/20 0.32
PPOX P50336 1/20 0.31
MEN1 O00255 1/20 0.30
PRKD3 O94806 1/20 0.30
EGFR P00533 1/20 0.30
PRKCG P05129 1/20 0.30
PRKCB P05771 1/20 0.30
MAPT P10636 1/20 0.30
SRC P12931 1/20 0.30
PRKCA P17252 1/20 0.30
PRKCH P24723 1/20 0.30
PRKCI P41743 1/20 0.30
PRKCE Q02156 1/20 0.30
KMT2A Q03164 1/20 0.30
PRKCQ Q04759 1/20 0.30
PRKCZ Q05513 1/20 0.30
PRKCD Q05655 1/20 0.30
PRKD1 Q15139 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424892 0.80 GRM5 (0.35) GRM5PPOX
SCHEMBL12424894 0.79 GRM5 (0.37) TGM2GRM5MEN1PRKD3EGFR
SCHEMBL12424859 0.75 CES2 (0.33) TGM2
SCHEMBL12424915 0.75 CA1 (0.31) TGM2
SCHEMBL12424887 0.73 PPOX (0.50) TGM2PPOXMAPT
SCHEMBL12424977 0.72
SCHEMBL12424871 0.71 TDP2 (0.46) TGM2GRM5MEN1PRKD3EGFR
SCHEMBL12424870 0.71 CA1 (0.38) MEN1MAPTKMT2A
SCHEMBL12424872 0.71 CA9 (0.40) TGM2GRM5MEN1PRKD3EGFR
SCHEMBL22625731 0.71 PTGS2 (0.44) MEN1PRKD3EGFRPRKCGPRKCB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed