SCHEMBL12424928

SCHEMBL12424928

O=C1NC(c2cc(F)cc(C(F)(F)F)c2)=C2C(=O)NC(c3cc(F)cc(C(F)(F)F)c3)=C12

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RXRA P19793 2/20 0.41
RXRB P28702 2/20 0.41
RXRG P48443 2/20 0.41
PGR P06401 1/20 0.37
PTGS1 P23219 1/20 0.33
TDP2 O95551 2/20 0.32
NOTUM Q6P988 2/20 0.31
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31
S1PR2 O95136 1/20 0.30
STK10 O94804 1/20 0.30
SLK Q9H2G2 1/20 0.30
IDH2 P48735 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12424970 0.89 RXRA (0.38) RXRARXRBRXRGTDP2NOTUM
SCHEMBL12424982 0.85 RXRA (0.38) RXRARXRBRXRGTDP2
SCHEMBL12424992 0.83 AKR1C3 (0.33) RXRARXRBRXRGTDP2NOTUM
SCHEMBL12424873 0.83 TGM2 (0.35) PGRPTGS1NOTUM
SCHEMBL12425001 0.82 NOTUM (0.32) RXRARXRBRXRGTDP2NOTUM
SCHEMBL12424995 0.81 TDP2 (0.43) RXRARXRBRXRGTDP2NOTUM
SCHEMBL12424976 0.79 NOTUM (0.44) RXRAPGRNOTUMSTK10SLK
SCHEMBL12424903 0.76 NOTUM (0.48) RXRAPGRNOTUMSTK10SLK
SCHEMBL12424997 0.76 NPY5R (0.42) PTGS1TDP2NOTUM
SCHEMBL12425000 0.75 TP53 (0.45) RXRAPGRNOTUMSTK10SLK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-7977670-B2 Organic transistor TOYO INK MFG. CO., LTD. (JP) 2011-07-12 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed
US-20100032657-A1 ORGANIC TRANSISTOR TOYO INK MFG CO., LTD (JP) 2010-02-11 US disclosed