Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | TLR2 | O60603 | 4/20 | 0.34 |
| ▸ | ACHE | P22303 | 7/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.32 |
| ▸ | MMP8 | P22894 | 1/20 | 0.32 |
| ▸ | MMP14 | P50281 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17449528 | 0.95 | THRB (0.43) | THRBTSHRTLR2ACHE | |
| SCHEMBL13324456 | 0.93 | TSHR (0.39) | THRBTSHRTLR2ACHE | |
| SCHEMBL17449527 | 0.89 | THRB (0.36) | THRBTSHRTLR2ACHE | |
| SCHEMBL16804279 | 0.86 | TSHR (0.36) | TSHR | |
| SCHEMBL17448868 | 0.85 | THRB (0.42) | THRBTSHRTLR2ACHE | |
| SCHEMBL14368422 | 0.84 | THRB (0.40) | THRBTSHRTLR2 | |
| SCHEMBL22522331 | 0.82 | ALDH1A1 (0.36) | — | |
| SCHEMBL19862506 | 0.82 | TSHR (0.30) | TSHR | |
| SCHEMBL15779947 | 0.82 | THRB (0.35) | THRBTSHRTLR2ACHEMMP9 | |
| SCHEMBL23002886 | 0.81 | TSHR (0.41) | TSHRTLR2ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8748647-B2 | Silane and silicic acid polycondensates with radicals containing branched-chain urethane, acid amide and/or carboxylic acid ester groups | Fraunhofer—Gesellschaft zur Föderung der angewandten Forschung e.V. (DE) | 2014-06-10 | — | — | US | disclosed |
| US-7977404-B2 | A polysiloxane resin substituted with the urethane group ending with a straight-chain or branched organically polymerizable group with (meth)acrylate residues; and a nanoparticulate filler | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2011-07-12 | — | — | US | disclosed |
| US-7932414-B2 | Silane and silicic acid polycondensates with radicals containing branched-chain urethane, acid amide and/or carboxylic acid ester groups | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. (DE) | 2011-04-26 | — | — | US | disclosed |
| US-20110082250-A1 | Silane and Silicic Acid Polycondensates with Radicals Containing Branched-Chain Urethane, Acid Amide and/or Carboxylic Acid Ester Groups | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) | 2011-04-07 | — | — | US | disclosed |
| US-20080187499-A1 | Tough, Long-Lasting Dental Composites | FRAUNHOFER-GESELLSCHAFT ZUR FORDERUNG DER ANGEWANDTEN FORSCHUNG E. V. (DE) | 2008-08-07 | — | — | US | disclosed |
| US-20070135572-A1 | Silane and silicic acid polycondensates with radicals containing branched-chain urethane, acid amide and/or carboxylic acid ester groups | FRAUNHOFER-GESELLSCHAFT ZUR FOERDERUNG DER ANGEWANDTEN FORSCHUNG E.V. | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110082250-A1 | Silane and Silicic Acid Polycondensates with Radicals Containing Branched-Chain Urethane, Acid Amide and/or Carboxylic Acid Ester Groups | ORC3, BCAT1, MSR1 | THRB 3405/4885TSHR 4007/4885TLR2 448/4885 |
| US-20080187499-A1 | Tough, Long-Lasting Dental Composites | LBR, ITGB1, TAS2R10 | THRB 137/4885TSHR 475/4885TLR2 1445/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.