Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GCGR | P47871 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 2/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12434731 | 0.79 | SLC6A9 (0.41) | SLC6A9ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL12434732 | 0.77 | L3MBTL1 (0.56) | SLC6A9TDP1ABCB1ALDH1A1KDM4E | |
| SCHEMBL7193788 | 0.77 | L3MBTL1 (0.56) | SLC6A9TDP1ABCB1ALDH1A1KDM4E | |
| SCHEMBL2608087 | 0.72 | SLC6A9 (0.41) | SLC6A9TDP1ALDH1A1KDM4EGAA | |
| SCHEMBL13559358 | 0.70 | SLC6A9 (0.42) | SLC6A9TDP1ALDH1A1KDM4EGAA | |
| SCHEMBL435975 | 0.70 | MEN1 (0.39) | SLC6A9TDP1ALDH1A1KDM4EGAA | |
| SCHEMBL14143089 | 0.68 | SLC6A2 (0.44) | SLC6A9TDP1ABCB1ALDH1A1KDM4E | |
| SCHEMBL10706138 | 0.67 | HRH3 (0.52) | SLC6A9ABCB1ALDH1A1POLBGCGR | |
| SCHEMBL10707183 | 0.66 | HRH3 (0.55) | SLC6A9ABCB1ALDH1A1POLBGCGR | |
| SCHEMBL25991088 | 0.65 | ALDH1A1 (0.50) | ALDH1A1GAACYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2353714-A1 | ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2011-08-10 | — | — | EP | disclosed |