Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7193788 | 1.00 | L3MBTL1 (0.56) | L3MBTL1SLC6A9TSHRPOLBKDM4E | |
| SCHEMBL11287435 | 0.79 | MTNR1A (0.56) | L3MBTL1POLBKDM4EGAALMNA | |
| SCHEMBL12434734 | 0.77 | SLC6A9 (0.50) | L3MBTL1SLC6A9TSHRPOLBKDM4E | |
| SCHEMBL12434733 | 0.77 | SLC6A9 (0.44) | L3MBTL1SLC6A9POLBKDM4EMAPT | |
| SCHEMBL27498873 | 0.77 | TSHR (0.51) | TSHRALDH1A1GAACYP1A2CYP2C19 | |
| SCHEMBL7187375 | 0.76 | L3MBTL1 (0.51) | L3MBTL1POLBALDH1A1CYP2C19 | |
| SCHEMBL2608087 | 0.76 | SLC6A9 (0.41) | L3MBTL1SLC6A9TSHRPOLBKDM4E | |
| SCHEMBL12074443 | 0.75 | L3MBTL1 (0.54) | L3MBTL1TSHRPOLBKDM4EALDH1A1 | |
| SCHEMBL9625233 | 0.75 | L3MBTL1 (0.54) | L3MBTL1TSHRPOLBKDM4EALDH1A1 | |
| SCHEMBL9366370 | 0.75 | ADRB2 (0.55) | KDM4EMAPTALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2353714-A1 | ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2011-08-10 | — | — | EP | disclosed |