Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MITF | O75030 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12434733 | 0.79 | SLC6A9 (0.44) | SLC6A9MAPTMEN1KMT2APOLB | |
| SCHEMBL12434734 | 0.77 | SLC6A9 (0.50) | SLC6A9MAPTMEN1KMT2APOLB | |
| SCHEMBL31090415 | 0.66 | CRHBP (0.66) | MAPTMEN1KMT2AERN1POLB | |
| SCHEMBL12826492 | 0.62 | POLB (0.52) | MAPTMEN1KMT2APOLBKDM4E | |
| SCHEMBL12434732 | 0.62 | L3MBTL1 (0.56) | SLC6A9MAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL7193788 | 0.62 | L3MBTL1 (0.56) | SLC6A9MAPTPOLBKDM4EALDH1A1 | |
| SCHEMBL8720249 | 0.62 | ALDH1A1 (0.46) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL10706138 | 0.61 | HRH3 (0.52) | SLC6A9POLBALDH1A1LMNAHRH3 | |
| SCHEMBL10693530 | 0.61 | TDP1 (0.58) | KDM4EALDH1A1SMN1; SMN2HRH3 | |
| SCHEMBL18175759 | 0.60 | KDM4E (0.61) | MEN1KMT2AKDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2353714-A1 | ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2011-08-10 | — | — | EP | disclosed |