Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.41 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2171378 | 0.87 | ALDH1A1 (0.43) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL24987703 | 0.85 | MAPT (0.47) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL12125525 | 0.85 | TSHR (0.59) | MAPTKMT2AMEN1ALDH1A1NPC1 | |
| SCHEMBL12125516 | 0.83 | PARP1 (0.44) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL23112279 | 0.83 | S100A4 (0.40) | MAPTKMT2AMEN1LMNAPOLB | |
| SCHEMBL13377058 | 0.82 | CYP2A6 (0.47) | MAPTKMT2ALMNACYP2A6ALDH1A1 | |
| SCHEMBL24252035 | 0.80 | HPGD (0.47) | MAPTKMT2AMEN1LMNAPKM | |
| SCHEMBL22000399 | 0.80 | ALDH1A1 (0.55) | MAPTKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL1909361 | 0.78 | CYP2A6 (0.48) | MAPTCYP2A6ALDH1A1PKMRAB9A | |
| SCHEMBL385514 | 0.78 | HSP90AA1 (0.60) | MAPTLMNAPOLBCYP2A6PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873291-B2 | Quinoline cGAS antagonist compounds | IMMUNESENSOR THERAPEUTICS, INC. (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM | 2023-11-09 | — | — | US | disclosed |
| EP-3534709-B1 | SUBSTITUTED SULFONYLAMIDE FOR COMBATING ANIMAL PESTS | BAYER AG (DE) | 2021-06-16 | — | — | EP | disclosed |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | BAYER AKTIENGESELLSCHAFT (DE) | 2020-11-03 | — | — | US | disclosed |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | BAYER AKTIENGESELLSCHAFT (DE) | 2019-09-05 | — | — | US | disclosed |
| US-20110178092-A1 | HIV-1 Protease Inhibitors | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2011-07-21 | — | — | US | disclosed |
| US-20110178092-A1 | HIV-1 Protease Inhibitors | UNIVERSITY OF MARYLAND, COLLEGE PARK | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178092-A1 | HIV-1 Protease Inhibitors | SERPINB1, PRSS1, TMPRSS4 | MAPT 1765/4885KMT2A 2108/4885MEN1 4587/4885 |
| US-11873291-B2 | Quinoline cGAS antagonist compounds | CGAS, GLS2, GLS | MAPT 3235/4885KMT2A 4371/4885MEN1 1514/4885 |
| US-20230357158-A1 | QUINOLINE cGAS ANTAGONIST COMPOUNDS | CGAS, GLS2, GLS | MAPT 3235/4885KMT2A 4371/4885MEN1 1514/4885 |
| US-20190269134-A1 | SUBSTITUTED SULFONYL AMIDES FOR CONTROLLING ANIMAL PESTS | MLYCD, STOM, DDT | MAPT 4320/4885KMT2A 380/4885MEN1 878/4885 |
| US-10820591-B2 | Substituted sulfonyl amides for controlling animal pests | MLYCD, STOM, DDT | MAPT 4320/4885KMT2A 380/4885MEN1 878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.