SCHEMBL12436486

SCHEMBL12436486

CC1(C)c2ccccc2N(c2cc(-c3ccccc3)cc(-c3ccccc3)c2)c2cc3c(cc21)N(c1nc(-c2ccccc2)nc(-c2ccccc2)n1)c1ccccc1C3(C)C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 3/20 0.33
▸ ITGB2 P05107 1/20 0.32
▸ ICAM1 P05362 1/20 0.32
▸ ITGAL P20701 1/20 0.32
▸ ADAMTS5 Q9UNA0 1/20 0.31
▸ MEN1 O00255 4/20 0.31
▸ MAPT P10636 4/20 0.31
▸ KMT2A Q03164 4/20 0.31
▸ HTT P42858 3/20 0.31
▸ LMNA P02545 2/20 0.31
▸ GAA P10253 2/20 0.31
▸ MAPK1 P28482 2/20 0.31
▸ ALDH1A1 P00352 2/20 0.31
▸ SMN1; SMN2 Q16637 1/20 0.31
▸ TDP1 Q9NUW8 1/20 0.31
▸ HPGD P15428 2/20 0.30
▸ KDM4E B2RXH2 1/20 0.30
▸ PSMD14 O00487 1/20 0.30
▸ CYP1A2 P05177 1/20 0.30
▸ POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19038681 0.90 L3MBTL1 (0.39) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL15832260 0.90 — —
SCHEMBL13231684 0.89 L3MBTL1 (0.38) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL21474019 0.88 ITGB2 (0.37) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL12435727 0.88 L3MBTL1 (0.35) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL13231677 0.86 L3MBTL1 (0.36) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL17278602 0.86 L3MBTL1 (0.38) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL17278601 0.86 L3MBTL1 (0.38) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL13231651 0.86 L3MBTL1 (0.40) L3MBTL1ITGB2ICAM1ITGALADAMTS5
SCHEMBL15490803 0.85 L3MBTL1 (0.44) L3MBTL1MEN1MAPTKMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-11917903-B2 Metal complexes UDC IRELAND LIMITED (IE) 2024-02-27 — — US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 — — US disclosed
US-20230320191-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-10-05 — — US disclosed
US-20230292596-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-09-14 — — US disclosed
US-20230292596-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2023-09-14 — — US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 — — US disclosed
US-20230271989-A1 METAL COMPLEXES UDC IRELAND LIMITED (IE) 2023-08-31 — — US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 — — US disclosed
US-11659763-B2 Metal complexes MERCK PATENT GMBH 2023-05-23 — — US disclosed
US-20160315268-A1 ORGANIC ELECTROLUMINESCENT DEVICE WITH THERMALLY ACTIVATED DELAYED FLUORESCENCE MATERIAL MERCK PATENT GMBH (DE) 2016-10-27 — — US disclosed
WO-2016124304-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2016-08-11 — — WO disclosed
US-20160155959-A1 Organic Electroluminescent Device MERCK PATENT GMBH (DE) 2016-06-02 — — US disclosed
US-20160155959-A1 Organic Electroluminescent Device MERCK PATENT GMBH (DE) 2016-06-02 — — US disclosed
US-20160093813-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2016-03-31 — — US disclosed
US-20160093813-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2016-03-31 — — US disclosed
US-20150340621-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-26 — — US disclosed
US-20150340621-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-26 — — US disclosed
WO-2014094964-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-06-26 — — WO disclosed
WO-2011093609-A1 NOVEL ORGANIC ELECTROLUMINESCENT COMPOUNDS AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME ROHM AND HAAS ELECTRONIC MATERIALS KOREA LTD. (KR) 2011-08-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230320191-A1 METAL COMPLEXES IMMT, MCU, SOD1 L3MBTL1 3259/4885ITGB2 805/4885ICAM1 221/4885
US-20230292596-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, EPCAM, L1CAM L3MBTL1 1208/4885ITGB2 1575/4885ICAM1 313/4885
US-20230271989-A1 METAL COMPLEXES AP3M1, AP1M1, AP2M1 L3MBTL1 2773/4885ITGB2 1828/4885ICAM1 555/4885
US-11659763-B2 Metal complexes IMMT, MCU, SOD1 L3MBTL1 3259/4885ITGB2 805/4885ICAM1 221/4885
US-11917903-B2 Metal complexes NCLN, BICRA, AP3M1 L3MBTL1 2532/4885ITGB2 1822/4885ICAM1 1103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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