Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 4/20 | 0.59 |
| ▸ | RORC | P51449 | 3/20 | 0.59 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.59 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 6/20 | 0.57 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.57 |
| ▸ | DHCR24 | Q15392 | 1/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.57 |
| ▸ | CRYAB | P02511 | 1/20 | 0.55 |
| ▸ | HMGCR | P04035 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.54 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17693794 | 0.95 | OSBP (0.60) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL17696316 | 0.91 | OSBP (0.63) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL1542632 | 0.89 | USP2 (0.61) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL1397890 | 0.86 | OSBP (0.58) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL1542841 | 0.82 | ATIC (0.48) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL29420066 | 0.82 | DHCR24 (0.56) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL19625268 | 0.82 | DHCR24 (0.56) | OSBPRORCOSBP2USP2LMNA | |
| SCHEMBL4142848 | 0.80 | POLA1 (0.54) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL9788710 | 0.78 | OSBP (0.89) | OSBPRORCOSBP2USP2LMNA | |
| Cholesterol SCHEMBL29222667 | 0.77 | OSBP (0.80) | OSBPRORCOSBP2USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180112245-A1 | METHOD AND COMPOSITION FOR BIOCATALYTIC PROTEIN-OLIGONUCLEOTIDE CONJUGATION AND PROTEIN-OLIGONUCLEOTIDE CONJUGATE | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK | 2018-04-26 | — | — | US | disclosed |
| US-20160109469-A1 | METHOD OF MEASURING LIPOPROTEIN'S CAPACITY TO ACCEPT CHOLESTEROL | SYSMEX CORPORATION (JP) | 2016-04-21 | — | — | US | disclosed |
| US-20110177156-A1 | Sterol-Modified Amphiphilic Lipids | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2011-07-21 | — | — | US | disclosed |
| WO-2009064696-A1 | STEROL-MODIFIED AMPHIPHILIC LIPIDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2009-05-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110177156-A1 | Sterol-Modified Amphiphilic Lipids | SREBF1, SREBF2, SGMS1 | OSBP 16/4885RORC 346/4885OSBP2 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.