Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 7/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437616 | 0.91 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1HPGDRXFP1 | |
| SCHEMBL298875 | 0.89 | KMT2A (0.40) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29360338 | 0.89 | KMT2A (0.40) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14121019 | 0.87 | LRRK2 (0.42) | MEN1KMT2AALDH1A1RXFP1LMNA | |
| SCHEMBL12437133 | 0.86 | TAS1R3 (0.40) | CYP1A2CYP2D6CYP2C19RXFP1S1PR3 | |
| SCHEMBL29360734 | 0.86 | KMT2A (0.39) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3703139 | 0.86 | KMT2A (0.39) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL16330798 | 0.85 | S1PR3 (0.52) | S1PR3S1PR1 | |
| SCHEMBL14120380 | 0.85 | TRPV1 (0.46) | KMT2AALDH1A1RXFP1S1PR3S1PR1 | |
| SCHEMBL28581106 | 0.84 | MEN1 (0.37) | MEN1KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531484-B1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-08-17 | — | — | EP | disclosed |
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA CROP PROTECTION LLC (US) | 2012-12-06 | — | — | US | disclosed |
| WO-2011095462-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120309812-A1 | INSECTICIDAL COMPOUNDS | ACHE, AADAC, NISCH | MEN1 2560/4885KMT2A 1531/4885F10 3691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.