Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.42 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437620 | 0.91 | MEN1 (0.46) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL14120380 | 0.91 | TRPV1 (0.46) | ALDH1A1KMT2AMAPTRXFP1KCNMA1 | |
| SCHEMBL17560976 | 0.86 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL16330798 | 0.86 | S1PR3 (0.52) | S1PR3S1PR1 | |
| SCHEMBL12437133 | 0.85 | TAS1R3 (0.40) | RXFP1KCNMA1S1PR3S1PR1RAB9A | |
| SCHEMBL18023968 | 0.85 | HDAC1 (0.42) | MEN1KMT2AS1PR3S1PR1RAB9A | |
| SCHEMBL12438374 | 0.83 | S1PR3 (0.39) | MEN1KMT2AS1PR3S1PR1NPC1 | |
| SCHEMBL12437132 | 0.80 | S1PR3 (0.40) | S1PR3S1PR1RAB9A | |
| SCHEMBL29360338 | 0.79 | KMT2A (0.40) | ALDH1A1MEN1KMT2AHPGDMAPT | |
| SCHEMBL298875 | 0.79 | KMT2A (0.40) | ALDH1A1MEN1KMT2AHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011095462-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | disclosed |