Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | EIF2S1 | P05198 | 3/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | EIF2AK3 | Q9NZJ5 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888055 | 0.91 | HPGD (0.35) | DHODHPDE4AMALT1ALOX5CAPN1 | |
| SCHEMBL13242831 | 0.91 | DHODH (0.35) | DHODHPDE4AMALT1ALOX5KCNH2 | |
| SCHEMBL782222 | 0.91 | DHODH (0.43) | DHODHPDE4AMALT1KCNH2CAPN1 | |
| SCHEMBL782232 | 0.91 | DHODH (0.43) | DHODHPDE4AMALT1KCNH2CAPN1 | |
| SCHEMBL14361041 | 0.91 | DHODH (0.43) | DHODHPDE4AMALT1KCNH2CAPN1 | |
| SCHEMBL13287802 | 0.91 | DHODH (0.43) | DHODHMALT1CHRNA7 | |
| SCHEMBL10028768 | 0.90 | DHODH (0.43) | DHODHPDE4AMALT1KCNH2CAPN1 | |
| SCHEMBL3086322 | 0.89 | DHODH (0.49) | DHODHPDE4AMALT1KCNH2CAPN1 | |
| SCHEMBL30078383 | 0.88 | DHODH (0.41) | DHODHPDE4AMALT1KCNH2CAPN1 | |
| SCHEMBL563173 | 0.88 | DHODH (0.41) | DHODHPDE4AMALT1KCNH2CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | SYNGENTA CROP PROTECTION LLC (US) | 2012-09-27 | — | — | US | disclosed |
| WO-2011095462-A1 | INSECTICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2011-08-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120245026-A1 | SPIRO FUSED 1-AMINO - PIPERDINE PYRROLIDINE DIONE DERIVATIVES WITH PESTICIDAL ACTIVITY | DDT, CAT, AQP1 | DHODH 211/4885PDE4A 382/4885MALT1 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.