SCHEMBL12440685

SCHEMBL12440685

COC1C(OC(C)C)OC(CO)C(O)C1O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 2/20 0.42
▸ ALDH1A1 P00352 1/20 0.42
▸ THRB P10828 1/20 0.42
▸ CA1 P00915 1/20 0.41
▸ CA2 P00918 1/20 0.41
▸ CA9 Q16790 1/20 0.41
▸ TYR P14679 6/20 0.40
▸ L3MBTL1 Q9Y468 1/20 0.40
▸ FGF1 P05230 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22224176 0.90 ALDH1A1 (0.43) ALDH1A1THRBCA1CA2CA9
SCHEMBL13716367 0.87 AMY2A (0.45) LGALS8CA1CA2CA9TYR
SCHEMBL16234072 0.87 AMY2A (0.45) LGALS8CA1CA2CA9TYR
SCHEMBL26448835 0.87 LGALS8 (0.46) LGALS8ALDH1A1THRBCA1CA2
SCHEMBL23705114 0.84 LGALS8 (0.51) LGALS8L3MBTL1FGF1
SCHEMBL20027477 0.84 L3MBTL1 (0.49) ALDH1A1THRBCA1CA2CA9
SCHEMBL14690973 0.84 L3MBTL1 (0.49) ALDH1A1THRBCA1CA2CA9
SCHEMBL22098622 0.84 LGALS8 (0.51) LGALS8L3MBTL1FGF1
SCHEMBL10388284 0.84 L3MBTL1 (0.49) ALDH1A1THRBCA1CA2CA9
SCHEMBL24943577 0.84 L3MBTL1 (0.49) ALDH1A1THRBCA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110177029-A1 O-LINKED GLYCOSYLATION USING N-ACETYLGLUCOSAMINYL TRANSFERASES NOVO NORDISK A/S (DK) 2011-07-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177029-A1 O-LINKED GLYCOSYLATION USING N-ACETYLGLUCOSAMINYL TRANSFERASES OGT, UGGT1, GALNT6 LGALS8 263/4885ALDH1A1 1060/4885THRB 3786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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