SCHEMBL12440977

SCHEMBL12440977

COc1cccc(COc2c(C)cc(C)cc2Br)c1

nearest known ligand 0.55

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MAOB P27338 10/20 0.55
MAPT P10636 4/20 0.51
L3MBTL1 Q9Y468 3/20 0.51
LMNA P02545 1/20 0.49
IDO1 P14902 2/20 0.49
AGXT P21549 2/20 0.49
THRA P10827 1/20 0.47
THRB P10828 1/20 0.47
ABCB1 P08183 1/20 0.46
HTR1A P08908 1/20 0.46
DRD2 P14416 1/20 0.46
KDM4E B2RXH2 1/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13429941 0.86 MAOB (0.52) MAOBMAPTIDO1AGXTTHRA
SCHEMBL12440973 0.86 MAOB (0.56) MAOBMAPTIDO1AGXTABCB1
SCHEMBL12514353 0.85 MAOB (0.51) MAOBIDO1AGXTTHRATHRB
SCHEMBL13429710 0.85 MAOB (0.51) MAOBMAPTIDO1AGXTTHRA
SCHEMBL9893668 0.84 MAOB (0.50) MAOBMAPTIDO1AGXTTHRA
SCHEMBL12440978 0.84 THRA (0.56) MAOBMAPTL3MBTL1LMNAIDO1
SCHEMBL13430102 0.82 MAOB (0.48) MAOBIDO1AGXTTHRATHRB
SCHEMBL12440971 0.82 MEN1 (0.55) MAOBMAPTL3MBTL1LMNATHRA
SCHEMBL12440963 0.82 MAOB (0.51) MAOBMAPTL3MBTL1LMNAIDO1
SCHEMBL12440957 0.82 THRA (0.59) MAOBMAPTL3MBTL1LMNAIDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 MAOB 2353/4885MAPT 456/4885L3MBTL1 4308/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.