SCHEMBL12440957

SCHEMBL12440957

Cc1cc(C)c(OCc2cccc(Cl)c2)c(Br)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRA P10827 3/20 0.59
THRB P10828 3/20 0.59
MAPT P10636 3/20 0.52
CYP3A4 P08684 3/20 0.52
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
LMNA P02545 2/20 0.52
CYP1A2 P05177 1/20 0.52
HSP90AA1 P07900 1/20 0.52
XBP1 P17861 1/20 0.52
CYP2C19 P33261 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
GRM5 P41594 4/20 0.50
L3MBTL1 Q9Y468 2/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
MAOB P27338 2/20 0.46
MRGPRX4 Q96LA9 1/20 0.45
IDO1 P14902 2/20 0.45
AGXT P21549 2/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10269141 0.90 GRM5 (0.56) THRATHRBCYP3A4GRM5KDM4E
SCHEMBL13429871 0.86 THRA (0.53) THRATHRBMAPTCYP3A4MEN1
SCHEMBL12440978 0.85 THRA (0.56) THRATHRBMAPTMEN1KMT2A
SCHEMBL12514201 0.85 THRA (0.55) THRATHRBMAPTCYP3A4MEN1
SCHEMBL13429702 0.84 THRA (0.51) THRATHRBMAPTCYP3A4MEN1
SCHEMBL9893602 0.84 ENPP2 (0.56) THRATHRBMAPTCYP3A4MEN1
SCHEMBL12440960 0.84 THRA (0.51) THRATHRBMAPTCYP3A4MEN1
SCHEMBL12440971 0.83 MEN1 (0.55) THRATHRBMAPTMEN1KMT2A
SCHEMBL12440963 0.83 MAOB (0.51) THRATHRBMAPTMEN1KMT2A
SCHEMBL12440977 0.82 MAOB (0.55) THRATHRBMAPTLMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9318706-B2 Laminated structure, method for producing same, and electronic element comprising same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2016-04-19 US disclosed
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110177312-A1 LAMINATED STRUCTURE, METHOD FOR PRODUCING SAME, AND ELECTRONIC ELEMENT COMPRISING SAME EPCAM, ITGA1, ITGB1 THRA 3000/4885THRB 3991/4885MAPT 456/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.