Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 20/20 | 0.42 |
| ▸ | CTSL | P07711 | 3/20 | 0.41 |
| ▸ | CTSB | P07858 | 3/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2229423 | 0.77 | CTSS (0.44) | CTSSCTSLCTSB | |
| SCHEMBL2229700 | 0.71 | CTSS (0.65) | CTSSCTSLCTSBCTSK | |
| SCHEMBL2228715 | 0.69 | CTSS (0.73) | CTSSCTSLCTSB | |
| SCHEMBL2228255 | 0.69 | CTSS (0.73) | CTSSCTSLCTSB | |
| SCHEMBL19817504 | 0.66 | SLC1A1 (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL19817505 | 0.66 | SLC1A1 (0.55) | CTSSCTSLCTSBCTSK | |
| SCHEMBL18484547 | 0.66 | ALDH1A1 (0.50) | CTSSCTSLCTSBCTSK | |
| SCHEMBL12445444 | 0.66 | CTSS (0.49) | CTSSCTSLCTSK | |
| SCHEMBL7334064 | 0.65 | REN (0.57) | — | |
| SCHEMBL8116438 | 0.65 | CA1 (0.55) | CTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895497-B2 | Cathepsin S inhibitors | DCB-USA, LLC (US) | 2014-11-25 | — | — | US | disclosed |
| US-20110166141-A1 | CATHEPSIN S INHIBITORS | DCB-USA, LLC (US) | 2011-07-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110166141-A1 | CATHEPSIN S INHIBITORS | CTSS, CTSV, CTSB | CTSS 1/4885CTSL 10/4885CTSB 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.