SCHEMBL1245024

SCHEMBL1245024

CCCCC/C(=C/c1ccccc1)CO

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.58
TDP1 Q9NUW8 1/20 0.57
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
ELANE P08246 1/20 0.39
EGFR P00533 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
EPHX2 P34913 1/20 0.38
TUBB4A P04350 2/20 0.38
TUBB P07437 2/20 0.38
TUBA3C P0DPH7 2/20 0.38
TUBA1B P68363 2/20 0.38
TUBA4A P68366 2/20 0.38
TUBB4B P68371 2/20 0.38
TUBB3 Q13509 2/20 0.38
TUBB2A Q13885 2/20 0.38
TUBB8 Q3ZCM7 2/20 0.38
TUBA3E Q6PEY2 2/20 0.38
TUBA1A Q71U36 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17629458 1.00 LMNA (0.58) LMNATDP1CES2CES1ELANE
SCHEMBL1171617 1.00 LMNA (0.58) LMNATDP1CES2CES1ELANE
SCHEMBL872839 1.00 LMNA (0.58) LMNATDP1CES2CES1ELANE
Alcohol SCHEMBL3314314 0.98 LMNA (0.57) LMNATDP1CES2CES1ELANE
SCHEMBL11783451 0.98 TDP1 (0.59) LMNATDP1CES2CES1EGFR
SCHEMBL12291966 0.95 LMNA (0.51) LMNATDP1CES2CES1ELANE
Benzyl Alcohol SCHEMBL28201687 0.92 LMNA (0.51) LMNATDP1CES2CES1MEN1
SCHEMBL30439628 0.91 LMNA (0.64) LMNATDP1CES2CES1EGFR
SCHEMBL30439792 0.89 TDP1 (0.65) LMNATDP1CES2CES1EGFR
SCHEMBL8741682 0.89 LMNA (0.62) LMNATDP1CES2CES1EGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117503637-A Composition for caring and relieving skin barrier, preparation method and application 露乐健康科技股份有限公司 2024-02-06 CN claimed
CN-115466505-B Silicon PU plastic material 邯郸市爱尚体育科技有限公司 2024-01-12 CN claimed
CN-116782794-A Dispensing package and method for controlled delivery of adhesive compositions 宝洁公司 2023-09-19 CN claimed
CN-116270278-A Composition for caring and relieving skin barrier, preparation method and application 露乐健康科技股份有限公司 2023-06-23 CN claimed
CN-115876897-A Method for simultaneously detecting multiple limited perfumes in cosmetics 汕头海关技术中心 2023-03-31 CN claimed
CN-115466505-A Nano water-based silicon PU plastic material 邯郸市爱尚体育科技有限公司 2022-12-13 CN claimed
CN-115154377-A Application of cedar bud extract in reducing essence irritation of infant skin care products and cedar bud extract skin care composition 露乐健康科技股份有限公司 2022-10-11 CN claimed
CN-110179172-B Consumable for an aerosol-generating device 菲利普莫里斯生产公司 2022-06-24 CN claimed
US-8592621-B2 Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease SYMRISE AG (DE) 2013-11-26 US claimed
WO-2011061719-A1 METHOD FOR FORMULATING PERFUME COMPOSITIONS HAVING HIGH LEVELS OF NATURAL INGREDIENTS AND NO DECLARED ALLERGENS, AND PERFUME COMPOSITION OBTAINED BY MEANS OF SUCH A METHOD DANILA NICOLAS (FR) 2011-05-26 WO claimed
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE SYMRISE GMBH CO. KG (DE) 2011-02-24 US claimed
WO-2025070466-A1 SEAMLESS CAPSULE FOR ORAL CAVITY 森下仁丹株式会社 2025-04-03 WO disclosed
CN-119235709-A Composition for caring and relieving sensitive skin and application of composition in cosmetics 露乐健康科技股份有限公司 2025-01-03 CN disclosed
CN-119235708-A Inula flower extract, preparation method thereof and cosmetic composition 太和康美(北京)中医研究院有限公司 2025-01-03 CN disclosed
CN-118518772-A Method for detecting 26 sensitization essences in disposable sanitary products 浙江方圆检测集团股份有限公司 2024-08-20 CN disclosed
US-20060292097-A1 Fragrance compositions comprising benzo[4,5]thieno{3,2-b]pyran-2-one FLEXITRAL, INC. 2006-12-28 US disclosed
EP-1705171-A1 Improved aromachemicals Flexitral, Inc. (US) 2006-09-27 EP disclosed
US-20060094640-A1 Aromachemicals FLEXITRAL, INC. 2006-05-04 US disclosed
US-20050119156-A1 Aromachemicals FLEXITRAL, INC. 2005-06-02 US disclosed
US-20050096852-A1 Method for increasing the stability and intensity of odorant molecules FLEXITRAL, INC. 2005-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060292097-A1 Fragrance compositions comprising benzo[4,5]thieno{3,2-b]pyran-2-one TAS2R5, TRPA1, TAS2R4 LMNA 3497/4885TDP1 2191/4885CES2 931/4885
US-20110045069-A1 PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE TAS1R2, TAS2R5, TAS2R1 LMNA 3996/4885TDP1 4364/4885CES2 3237/4885
US-20050096852-A1 Method for increasing the stability and intensity of odorant molecules OR51E2, OR10J3, ZKSCAN2 LMNA 4879/4885TDP1 4773/4885CES2 4666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.