Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24183917 | 0.91 | KDM4E (0.34) | USP2MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL25907556 | 0.82 | MAPT (0.34) | MAPTCYP1A2CYP2C19 | |
| SCHEMBL29110057 | 0.80 | — | — | |
| SCHEMBL29110061 | 0.80 | — | — | |
| SCHEMBL2721908 | 0.79 | KDM4E (0.33) | MAPTTSHRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL28685310 | 0.79 | KDM1A (0.32) | — | |
| Fenoxasulfone SCHEMBL2470273 | 0.78 | SMN1; SMN2 (0.35) | MAPTTSHRKDM4EALDH1A1CYP1A2 | |
| Fenoxasulfone SCHEMBL29489596 | 0.78 | SMN1; SMN2 (0.35) | MAPTTSHRKDM4EALDH1A1CYP1A2 | |
| SCHEMBL28704580 | 0.67 | MAPK1 (0.41) | MAPTKDM4EALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL2721905 | 0.67 | HTR2C (0.33) | MAPTKDM4EALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230234947-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE, FENOXASULFONE AND VARIOUS SULFONE ANALOGS OF 5,5-DIMETHYL-4H-1,2-OXAZOLE | ADAMA AGAN LTD. (IL) | 2023-07-27 | — | — | US | disclosed |
| EP-4177244-A2 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE AND FENOXASULFONE | Adama Agan Ltd. (IL) | 2023-05-10 | — | — | EP | disclosed |
| EP-4177245-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF FENOXASULFONE | Adama Agan Ltd. (IL) | 2023-05-10 | — | — | EP | disclosed |
| EP-4177252-A2 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE, FENOXASULFONE AND VARIOUS SULFONE ANALOGS OF 5,5-DIMETHYL-4H-1,2-OXAZOLE | Adama Agan Ltd. (IL) | 2023-05-10 | — | — | EP | disclosed |
| WO-2022009044-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE, FENOXASULFONE AND VARIOUS SULFONE ANALOGS OF 5,5-DIMETHYL-4H-1,2-OXAZOLE | ADAMA AGAN LTD. (IL) | 2022-01-13 | — | — | WO | disclosed |
| EP-3936503-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE, FENOXASULFONE AND VARIOUS SULFONE ANALOGS OF 5,5-DIMETHYL-4H-1,2-OXAZOLE | Adama Agan Ltd. (IL) | 2022-01-12 | — | — | EP | disclosed |
| US-8921572-B2 | Method for producing 5,5-disubstituted 4,5-dihydroisoxazol-3-thiocarboxamidine salts | BASF SE (DE) | 2014-12-30 | — | — | US | disclosed |
| US-8921572-B2 | Method for producing 5,5-disubstituted 4,5-dihydroisoxazol-3-thiocarboxamidine salts | BASF SE (DE) | 2014-12-30 | — | — | US | disclosed |
| US-20120264947-A1 | Method for Producing 5,5-Disubstituted 4,5-Dihydroisoxazol-3-Thiocarboxamidine Salts | BASF SE (DE) | 2012-10-18 | — | — | US | disclosed |
| US-20120264947-A1 | Method for Producing 5,5-Disubstituted 4,5-Dihydroisoxazol-3-Thiocarboxamidine Salts | BASF SE (DE) | 2012-10-18 | — | — | US | disclosed |
| US-20120238760-A1 | Method for Producing 5,5-Disubstituted 2-Isoxazolines | BASF SE (DE) | 2012-09-20 | — | — | US | disclosed |
| US-20120238760-A1 | Method for Producing 5,5-Disubstituted 2-Isoxazolines | BASF SE (DE) | 2012-09-20 | — | — | US | disclosed |
| WO-2011063842-A1 | METHOD FOR PRODUCING 5,5-DISUBSTITUTED 4,5-DIHYDROISOXAZOL-3-THIOCARBOXAMIDINE SALTS | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
| WO-2011063843-A1 | METHOD FOR PRODUCING 5,5-DISUBSTITUTED 2-ISOXAZOLINES | BASF SE (DE) | 2011-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234947-A1 | PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PYROXASULFONE, FENOXASULFONE AND VARIOUS SULFONE ANALOGS OF 5,5-DIMETHYL-4H-1,2-OXAZOLE | TST, TXN2, PRDX1 | USP2 3403/4885MAPT 4809/4885TSHR 465/4885 |
| US-20120264947-A1 | Method for Producing 5,5-Disubstituted 4,5-Dihydroisoxazol-3-Thiocarboxamidine Salts | DHX15, DHX35, HDHD5 | USP2 1865/4885MAPT 4363/4885TSHR 32/4885 |
| US-20120238760-A1 | Method for Producing 5,5-Disubstituted 2-Isoxazolines | CBR3, CBR1, CYP3A5 | USP2 2284/4885MAPT 4725/4885TSHR 3098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.