SCHEMBL1245131

SCHEMBL1245131

CC(CN)CCNC(C)(C)CO

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19124975 0.79 ALDH1A1 (0.37)
SCHEMBL11501604 0.77 LMNA (0.46)
SCHEMBL11501579 0.73 ALOX15 (0.55)
SCHEMBL9638094 0.72 HTT (0.38)
SCHEMBL9516212 0.70 CASP2 (0.36)
SCHEMBL7117040 0.69 PKM (0.33)
SCHEMBL15996288 0.68 PKM (0.31)
SCHEMBL12927516 0.68 HTT (0.35)
SCHEMBL1457911 0.68
SCHEMBL4782050 0.68 HTT (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11583608-B2 Wound dressings, methods of using the same and methods of forming the same NOVAN, INC. (US) 2023-02-21 US claimed
US-20180214598-A1 WOUND DRESSINGS, METHODS OF USING THE SAME AND METHODS OF FORMING THE SAME LIGAND PHARMACEUTICALS INCORPORATED 2018-08-02 US claimed
EP-2467173-A2 WOUND DRESSINGS, METHODS OF USING THE SAME AND METHODS OF FORMING THE SAME Novan, Inc. (US) 2012-06-27 EP claimed
US-20120136323-A1 Wound Dressings, Methods of Using the Same and Methods of Forming the Same LIGAND PHARMACEUTICALS INCORPORATED 2012-05-31 US claimed
WO-2011022680-A2 WOUND DRESSINGS, METHODS OF USING THE SAME AND METHODS OF FORMING THE SAME NOVAN, INC. (US) 2011-02-24 WO claimed
US-6506811-B2 Carbamate solutions BASF AKTIENGESELLSCHAFT (DE) 2003-01-14 US claimed
US-11583608-B2 Wound dressings, methods of using the same and methods of forming the same NOVAN, INC. (US) 2023-02-21 US disclosed
EP-2467173-B1 WOUND DRESSINGS, METHODS OF USING THE SAME AND METHODS OF FORMING THE SAME NOVAN INC (US) 2019-04-24 EP disclosed
US-20180214598-A1 WOUND DRESSINGS, METHODS OF USING THE SAME AND METHODS OF FORMING THE SAME LIGAND PHARMACEUTICALS INCORPORATED 2018-08-02 US disclosed
US-9919072-B2 Wound dressings, methods of using the same and methods of forming the same NOVAN, INC. (US) 2018-03-20 US disclosed
EP-2467173-A2 WOUND DRESSINGS, METHODS OF USING THE SAME AND METHODS OF FORMING THE SAME Novan, Inc. (US) 2012-06-27 EP disclosed
US-20120136323-A1 Wound Dressings, Methods of Using the Same and Methods of Forming the Same LIGAND PHARMACEUTICALS INCORPORATED 2012-05-31 US disclosed
WO-2011022680-A2 WOUND DRESSINGS, METHODS OF USING THE SAME AND METHODS OF FORMING THE SAME NOVAN, INC. (US) 2011-02-24 WO disclosed
EP-1000955-B1 Carbamate solutions BASF AG (DE) 2005-04-27 EP disclosed
US-6506811-B2 Carbamate solutions BASF AKTIENGESELLSCHAFT (DE) 2003-01-14 US disclosed
US-20020133040-A1 Carbamate solutions BASF AKTIENGESELLSCHAFT 2002-09-19 US disclosed
US-6316662-B1 BLOWING AGENTS FOR POLYURETHANE FOAMS BASF AKTIENGESELLSCHAFT (DE) 2001-11-13 US disclosed
EP-1000955-A1 Carbamate solutions BASF AKTIENGESELLSCHAFT (DE) 2000-05-17 EP disclosed