Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.60 |
| ▸ | PPARD | Q03181 | 3/20 | 0.60 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.54 |
| ▸ | QDPR | P09417 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL356702 | 0.98 | PPARG (0.59) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL29664322 | 0.97 | PPARG (0.60) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL3690573 | 0.93 | PPARG (0.64) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL29682746 | 0.83 | PPARG (0.59) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL28764968 | 0.83 | PPARD (0.63) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL10495514 | 0.83 | PPARG (0.59) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL18555689 | 0.81 | ALDH1A1 (0.55) | NR3C1ALDH1A1GAA | |
| SCHEMBL31546100 | 0.81 | ALOX5 (0.57) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL11588846 | 0.81 | PTPN1 (0.57) | PPARGPPARDALOX5PTPN1CYP3A4 | |
| SCHEMBL30474578 | 0.81 | PTPN1 (0.57) | PPARGPPARDALOX5PTPN1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592621-B2 | Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease | SYMRISE AG (DE) | 2013-11-26 | — | — | US | claimed |
| US-20110045069-A1 | PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE | SYMRISE GMBH CO. KG (DE) | 2011-02-24 | — | — | US | claimed |
| EP-2292224-B1 | Derivatives of lactiosole for preventing or treating diabetes | SYMRISE AG (DE) | 2018-03-07 | — | — | EP | disclosed |
| US-20160168315-A1 | MODIFIED OLIGOESTERS AND MANUFACTURE METHODS OF THE OLIGOESTERS | ANHIDRIDOS Y DERIVADOS DE COLOMBIA S.A. ANDERCOL (CO) | 2016-06-16 | — | — | US | disclosed |
| US-8592621-B2 | Precursor compounds of sweet taste receptor antagonists for the prevention or treatment of disease | SYMRISE AG (DE) | 2013-11-26 | — | — | US | disclosed |
| EP-2292224-A1 | Precursor compounds of sweet receptor antagonists for preventing or treating diabetes | Symrise AG (DE) | 2011-03-09 | — | — | EP | disclosed |
| US-20110045069-A1 | PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE | SYMRISE GMBH CO. KG (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160168315-A1 | MODIFIED OLIGOESTERS AND MANUFACTURE METHODS OF THE OLIGOESTERS | OSTC, OSGEP, PUF60 | PPARG 2563/4885PPARD 2346/4885ALOX5 117/4885 |
| US-20110045069-A1 | PRECURSOR COMPOUNDS OF SWEET TASTE RECEPTOR ANTAGONISTS FOR THE PREVENTION OR TREATMENT OF DISEASE | TAS1R2, TAS2R5, TAS2R1 | PPARG 79/4885PPARD 127/4885ALOX5 1702/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.