SCHEMBL1245779

SCHEMBL1245779

CC(=O)OC1C(=O)c2c(O)cc(O)cc2OC1c1ccc(O)c(O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 4/20 0.66
▸ KMT2A Q03164 4/20 0.66
▸ MAPT P10636 5/20 0.65
▸ CYP3A4 P08684 5/20 0.65
▸ ALOX15 P16050 5/20 0.65
▸ HSD17B10 Q99714 4/20 0.65
▸ RECQL P46063 3/20 0.65
▸ POLB P06746 3/20 0.65
▸ KDM4E B2RXH2 3/20 0.65
▸ GAA P10253 3/20 0.65
▸ CYP1A2 P05177 2/20 0.65
▸ MAPK1 P28482 2/20 0.65
▸ SOST Q9BQB4 2/20 0.65
▸ ALOX12 P18054 2/20 0.65
▸ HIF1A Q16665 2/20 0.65
▸ NFKB1 P19838 1/20 0.65
▸ P4HB P07237 1/20 0.62
▸ THRB P10828 1/20 0.52
▸ HTT P42858 1/20 0.52
▸ BLM P54132 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30080341 1.00 MEN1 (0.66) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL2119758 1.00 MEN1 (0.66) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL29378078 1.00 MEN1 (0.66) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL27152643 0.91 MEN1 (0.65) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL14894623 0.91 MEN1 (0.65) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL23085395 0.91 MEN1 (0.65) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL23085410 0.89 MEN1 (0.67) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL10610491 0.89 MEN1 (0.67) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL31162834 0.88 SOST (0.63) MEN1KMT2AMAPTCYP3A4ALOX15
SCHEMBL13287803 0.88 SOST (0.63) MEN1KMT2AMAPTCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 829 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12568998-B2 Flavouring composition with balanced taste profile SYMRISE AG (DE) 2026-03-10 — — US claimed
EP-4694703-A1 ACYLATED DIHYDROCHALCONES, METHODS OF PRODUCTION AND USES THEREOF Symrise AG (DE) 2026-02-18 — — EP claimed
US-20260009063-A1 HIGH-PURITY STEVIOL GLYCOSIDES PURECIRCLE SDN BHD (MY) 2026-01-08 — — US claimed
EP-4444108-B1 ALDEHYDE MIXTURES FOR FLAVOUR IMPROVEMENT SYMRISE AG (DE) 2025-09-10 — — EP claimed
US-12378590-B2 High-purity steviol glycosides PURECIRCLE USA INC. (US) 2025-08-05 — — US claimed
EP-4551583-A1 HIGH-PURITY STEVIOL GLYCOSIDES PureCircle SDN BHD (MY) 2025-05-14 — — EP claimed
CN-119924491-A Flavoring composition with balanced taste characteristics 西姆莱斯有限公司 2025-05-06 — — CN claimed
CN-112626154-B High purity steviol glycosides 谱赛科有限责任公司 2025-03-14 — — CN claimed
WO-2025048633-A2 HIGH-PURITY STEVIOL GLYCOSIDES PURECIRCLE SDN. BHD. (MY) 2025-03-06 — — WO claimed
US-20240407414-A1 DIHYDROCHALCONE DERIVATIVES SYMRISE AG (DE) 2024-12-12 — — US claimed
US-20110158919-A1 AROMA COMPOSITION COMPRISING O-COUMARIC ACID TO REDUCE OR SUPPRESS UNDESIRABLE TASTE IMPRESSIONS OF SWEETENERS SYMRISE AG (DE) 2011-06-30 — — US claimed
US-20110076239-A1 REDUCED-SWEETENER PRODUCTS, FLAVORING MIXTURES FOR SAID REDUCED-SWEETENER PRODUCTS AND PROCESS FOR THE PRODUCTION OF PRODUCTS OF THIS TYPE SYMRISE AG (DE) 2011-03-31 — — US claimed
EP-2298084-A1 Sweetener-reduced products, aromatic mixtures for same and method of producing such products Symrise AG (DE) 2011-03-23 — — EP claimed
EP-2220945-A1 Aroma composition to reduce or suppress undesirable bitter and astringent taste impressions of sweeteners Symrise GmbH & Co. KG (DE) 2010-08-25 — — EP claimed
US-20100151055-A1 Aroma Composition to Reduce or Suppress Undesirable Bitter and Astringent Taste Impressions of Sweeteners SYMRISE GMBH & CO. KG (DE) 2010-06-17 — — US claimed
US-20070082105-A1 Polysaccharide sweetener compounds, process for manufacture, and method of selecting components for polysaccharide sweetener compounds based on user specific sweetener applications QUANTUM FOOD DESIGN, LLC. 2007-04-12 — — US claimed
WO-2007033278-A2 DISACHARIDE SWEETNER COMPOUNDS, PROCESS FOR MANUFACTURE, AND METHOD OF SELECTING COMPONENTS FOR DISACHARIDE SWEETNER COMPOUNDS BASED ON USER QUANTUM FOOD DESIGN, LLC. (US) 2007-03-22 — — WO claimed
WO-2007033277-A2 POLYSACCHARIDE SWEETENER COMPOUNDS, PROCESS FOR MANUFACTURE, AND METHOD OF SELECTING COMPONENTS FOR POLYSACCHARIDE SWEETENER COMPOUNDS BASED ON USER SPECIFIC SWEETENER APPLICATIONS QUANTUM FOOD DESIGN, LLC. (US) 2007-03-22 — — WO claimed
US-20070059422-A1 Disaccharide sweetener compounds, process for manufacture, and method of selecting components for dissacaride sweetener compounds based on user specific sweetener applications QUANTUM FOOD DESIGN, LLC. 2007-03-15 — — US claimed
WO-1988008256-A1 DIHYDROFLAVONOL DERIVATIVES USEFUL AS SWEETENERS UNIVERSITY PATENTS, INC. (US) 1988-11-03 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12568998-B2 Flavouring composition with balanced taste profile TAS2R20, TAS2R50, TAS2R40 MEN1 1082/4885KMT2A 4340/4885MAPT 3611/4885
US-20240407414-A1 DIHYDROCHALCONE DERIVATIVES TAS2R20, TAS2R50, TAS2R60 MEN1 1485/4885KMT2A 3445/4885MAPT 3287/4885
US-20260009063-A1 HIGH-PURITY STEVIOL GLYCOSIDES RFT1, TAS2R7, ACAT2 MEN1 2791/4885KMT2A 2794/4885MAPT 586/4885
US-20110076239-A1 REDUCED-SWEETENER PRODUCTS, FLAVORING MIXTURES FOR SAID REDUCED-SWEETENER PRODUCTS AND PROCESS FOR THE PRODUCTION OF PRODUCTS OF THIS TYPE TAS2R30, TAS2R40, TAS2R60 MEN1 1685/4885KMT2A 4039/4885MAPT 2916/4885
US-12378590-B2 High-purity steviol glycosides SI, TAS2R40, TAS2R7 MEN1 1295/4885KMT2A 1142/4885MAPT 4725/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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