Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 4/20 | 0.35 |
| ▸ | CNR2 | P34972 | 4/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10871016 | 0.92 | THRB (0.46) | KDM4EALDH1A1HPGDTHRBPOLB | |
| SCHEMBL12458561 | 0.87 | THRB (0.38) | KDM4EALDH1A1HPGDTHRBPOLB | |
| SCHEMBL10040400 | 0.85 | IDO1 (0.44) | KDM4EALDH1A1HPGDTHRBPOLB | |
| SCHEMBL14001875 | 0.85 | KDM4E (0.41) | KDM4EALDH1A1HPGDTHRBPOLB | |
| SCHEMBL2033775 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1HPGDTDP1TSHR | |
| SCHEMBL29791099 | 0.83 | KDM4E (0.58) | KDM4EALDH1A1HPGDTDP1TSHR | |
| SCHEMBL10580556 | 0.81 | THRB (0.50) | KDM4EALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL15347409 | 0.81 | HPGDS (0.44) | ALDH1A1THRBPOLBAPEX1HTT | |
| SCHEMBL27862419 | 0.81 | L3MBTL1 (0.48) | KDM4EALDH1A1THRBPOLBAPEX1 | |
| SCHEMBL10064078 | 0.80 | IDO1 (0.55) | KDM4EALDH1A1HPGDTHRBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8900479-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2014-12-02 | — | — | US | disclosed |
| US-8900479-B2 | Liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2014-12-02 | — | — | US | disclosed |
| US-20120236246-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-09-20 | — | — | US | disclosed |
| US-20120236246-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC PETROCHEMICAL CORPORATION (JP) | 2012-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120236246-A1 | LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | LASP1, VCL, NLK | KDM4E 3806/4885ALDH1A1 4255/4885HPGD 4064/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.