Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | GLA | P06280 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopenthiazide SCHEMBL30561852 | 0.81 | LMNA (1.00) | LMNACYP2C9ADRA2BKDM4EHTT | |
| Cyclopenthiazide SCHEMBL49142 | 0.81 | LMNA (1.00) | LMNACYP2C9ADRA2BKDM4EHTT | |
| SCHEMBL29132641 | 0.80 | LMNA (0.98) | LMNACYP2C9ADRA2BKDM4EHTT | |
| SCHEMBL30561876 | 0.80 | LMNA (0.98) | LMNACYP2C9ADRA2BKDM4EHTT | |
| Cyclopenthiazide SCHEMBL9505656 | 0.79 | LMNA (0.96) | LMNACYP2C9ADRA2BKDM4EHTT | |
| Clopamide SCHEMBL124598 | 0.79 | KDM4E (1.00) | LMNAKDM4EHTTGLAMAPT | |
| Clopamide SCHEMBL1650071 | 0.79 | KDM4E (1.00) | LMNAKDM4EHTTGLAMAPT | |
| Clopamide SCHEMBL28086094 | 0.78 | LMNA (0.68) | LMNAKDM4EHTTGLAMAPT | |
| Cyclopenthiazide SCHEMBL3137567 | 0.75 | LMNA (0.69) | LMNACYP2C9ADRA2BKDM4EHTT | |
| Cyclopenthiazide SCHEMBL13723122 | 0.74 | LMNA (0.85) | LMNACYP2C9ADRA2BKDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109475645-A | MicroRNA composition and its preparation and application | 先进瑞金医疗技术有限公司 | 2019-03-15 | — | — | CN | disclosed |