Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | RAB9A | P51151 | 8/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17954070 | 0.94 | NPC1 (0.58) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL17954037 | 0.91 | NPC1 (0.54) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL16693725 | 0.90 | NPC1 (0.59) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2146923 | 0.88 | NPC1 (0.51) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL31267541 | 0.87 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL29494818 | 0.87 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL258759 | 0.87 | NPC1 (0.66) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2146883 | 0.87 | NPC1 (0.50) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL17576047 | 0.87 | NPC1 (0.50) | NPC1RAB9APOLBLMNAKDM4E | |
| SCHEMBL2146554 | 0.85 | NPC1 (0.64) | NPC1RAB9APOLBLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8895754-B2 | Process to make UV radiation absorbing 2-phenyl-1,2,3,-benzotriazoles | DSM IP ASSETS B.V. (NL) | 2014-11-25 | — | — | US | disclosed |
| US-8895754-B2 | Process to make UV radiation absorbing 2-phenyl-1,2,3,-benzotriazoles | DSM IP ASSETS B.V. (NL) | 2014-11-25 | — | — | US | disclosed |
| US-8883829-B2 | 2-phenyl-1,2,3-benzotriazoles for UV radiation absorbance | DSM IP ASSETS B.V. (NL) | 2014-11-11 | — | — | US | disclosed |
| US-8883829-B2 | 2-phenyl-1,2,3-benzotriazoles for UV radiation absorbance | DSM IP ASSETS B.V. (NL) | 2014-11-11 | — | — | US | disclosed |
| US-20130142737-A1 | 2-PHENYL- 1,2,3- BENZOTRIAZOLES FOR UV RADIATION ABSORBANCE | DSM IP ASSETS B.V. (NL) | 2013-06-06 | — | — | US | disclosed |
| US-20130142737-A1 | 2-PHENYL- 1,2,3- BENZOTRIAZOLES FOR UV RADIATION ABSORBANCE | DSM IP ASSETS B.V. (NL) | 2013-06-06 | — | — | US | disclosed |
| US-20120302760-A1 | NOVEL PROCESS | DSM IP ASSETS B.V. (NL) | 2012-11-29 | — | — | US | disclosed |
| US-20120302760-A1 | NOVEL PROCESS | DSM IP ASSETS B.V. (NL) | 2012-11-29 | — | — | US | disclosed |
| WO-2011086124-A1 | 2 - PHENYL - 1, 2, 3 - BENZOTRIAZOLES FOR UV RADIATION ABSORBANCE | DSM IP ASSETS B.V. (NL) | 2011-07-21 | — | — | WO | disclosed |
| WO-2011086127-A1 | PROCESS TO MAKE UV RADIATION ABSORBING 2 - PHENYL - 1, 2, 3 - BENZOTRIAZOLES | DSM IP ASSETS B.V. (NL) | 2011-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130142737-A1 | 2-PHENYL- 1,2,3- BENZOTRIAZOLES FOR UV RADIATION ABSORBANCE | CCNL2, CYP1A1, CYP4Z1 | NPC1 3345/4885RAB9A 4272/4885POLB 1640/4885 |
| US-20120302760-A1 | NOVEL PROCESS | GABBR1, TPST2, GABBR2 | NPC1 4412/4885RAB9A 4545/4885POLB 1689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.