SCHEMBL124617

SCHEMBL124617

Fc1ccc2ccccc2n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCF1 P14598 3/20 0.52
CYP1A2 P05177 2/20 0.52
NOS2 P35228 1/20 0.52
BACE1 P56817 1/20 0.52
CA12 O43570 1/20 0.52
CA9 Q16790 1/20 0.52
MAPT P10636 5/20 0.48
ALDH1A1 P00352 5/20 0.48
HPGD P15428 3/20 0.48
GLA P06280 1/20 0.48
ACHE P22303 1/20 0.48
NPC1 O15118 8/20 0.46
RAB9A P51151 8/20 0.46
KDM4E B2RXH2 4/20 0.46
PKM P14618 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
LMNA P02545 2/20 0.46
NFKB1 P19838 2/20 0.46
NFKB2 Q00653 2/20 0.46
RELA Q04206 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29862377 1.00 NCF1 (0.52) NCF1CYP1A2NOS2BACE1CA12
SCHEMBL19219874 1.00 NCF1 (0.52) NCF1CYP1A2NOS2BACE1CA12
Benzene SCHEMBL27864621 0.97 NCF1 (0.50) NCF1CYP1A2NOS2BACE1CA12
Hydrochloric Acid SCHEMBL6529182 0.97 NCF1 (0.50) NCF1CYP1A2NOS2BACE1CA12
Quinoline SCHEMBL28157094 0.87 ALDH1A1 (0.68) NCF1CYP1A2NOS2BACE1CA12
SCHEMBL17962365 0.87 NCF1 (0.47) NCF1CYP1A2NOS2BACE1CA12
Acetone SCHEMBL22352606 0.87 KDM4E (0.50) NCF1CYP1A2NOS2BACE1MAPT
Benzenesulfonamide SCHEMBL20358013 0.80 CA1 (0.53) NCF1NOS2BACE1CA12CA9
Hydrochlorthiazide SCHEMBL28012369 0.80 RAB9A (0.39) NCF1CYP1A2NOS2BACE1CA12
SCHEMBL18092688 0.78 CA12 (0.65) CA12CA9ALDH1A1HPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260144251-A1 ANTIMICROBIAL NANOCLAYS COMPRISING CATIONIC ANTIMICROBIALS, METHOD OF PREPARATION AND USES THEREOF POLYAMYNA NANOTECH INC. (CA) 2026-05-28 US claimed
CN-117865932-B Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity BEIJING UNIVERSITY OF CHEMICAL TECHNOLOGY (CN) 2026-05-26 CN claimed
US-12564575-B2 Early management, mitigation and prevention of sepsis and sepsis-like syndromes, including neo-natal ARDS due to infection, injury or iatrogenesis OPHIREX, INC (US) 2026-03-03 US claimed
CN-119842078-A Polysulfone resin, preparation method thereof and polymer product 深圳市沃特新材料股份有限公司 2025-04-18 CN claimed
CN-119221207-A Fluorescent flexible fiber membrane dosimeter and preparation method and application thereof 南京航空航天大学 2024-12-31 CN claimed
US-20240390375-A1 METHODS AND COMPOSITIONS FOR TREATING VIRAL OR VIRALLY-INDUCED CONDITIONS Viracta Subsidiary, Inc. (US) 2024-11-28 US claimed
CN-118922081-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-11-08 CN claimed
CN-117865932-A Preparation method of benzothiophene sulfone compound with medicinal and fluorescent activity 北京化工大学 2024-04-12 CN claimed
CN-117320552-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2023-12-29 CN claimed
EP-4255994-A1 CLEAR COATING ANTIMICROBIAL COMPOSITIONS, METHODS OF PREPARATION, AND USES THEREOF FOR CONFERRING ANTIMICROBIAL ACTIVITY TO A SURFACE Polyamyna Nanotech Inc. (CA) 2023-10-11 EP claimed
EP-1250116-A1 PHARMACEUTICAL AND COSMETIC CARRIER OR COMPOSITION FOR TOPICAL APPLICATION Thixo Ltd. (IL) 2002-10-23 EP claimed
WO-2002074290-A2 DERMATOLOGICAL PREPARATIONS CONTAINING A NSAID AGIS INDUSTRIES (1983) LTD. (IL) 2002-09-26 WO claimed
EP-1194124-A1 TASTE MASKED COMPOSITIONS Ranbaxy Laboratories Limited (IN) 2002-04-10 EP claimed
WO-2001051014-A1 PHARMACEUTICAL AND COSMETIC CARRIER OR COMPOSITION FOR TOPICAL APPLICATION THIXO LTD (IL) 2001-07-19 WO claimed
WO-2000076479-A1 TASTE MASKED COMPOSITIONS RANBAXY LABORATORIES LIMITED (IN) 2000-12-21 WO claimed
EP-0641341-B1 METHOD FOR PREPARING BENZO [b]NAPHTHYRIDINES RHONE POULENC RORER SA (FR) 2000-03-01 EP claimed
US-5798115-A BIOCOMPATIBLE POLYMER COMPRISING AN ACTIVE DRUG ON POLYMER BACKBONE; BIODEGRADABLE, RELEASING THE DRUG INTERFACE BIOLOGICS (CA) 1998-08-25 US claimed
US-5776948-A BACTERICIDE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1998-07-07 US claimed
US-5484921-A Process for preparing benzo[b]naphthyridines LABORATOIRE ROGER BELLON (FR) 1996-01-16 US claimed
EP-0664288-A1 FLUOROQUINOLINE DERIVATIVE CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 1995-07-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260144251-A1 ANTIMICROBIAL NANOCLAYS COMPRISING CATIONIC ANTIMICROBIALS, METHOD OF PREPARATION AND USES THEREOF KLF10, SLC11A2, SLC7A11 NCF1 968/4885CYP1A2 4682/4885NOS2 1129/4885
US-12564575-B2 Early management, mitigation and prevention of sepsis and sepsis-like syndromes, including neo-natal ARDS due to infection, injury or iatrogenesis PLA2G12A, PLA2G3, PLA2G1B NCF1 2792/4885CYP1A2 1315/4885NOS2 2558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.